Strategies for Organic Drug Synthesis and Design / Edition 1 available in Hardcover
- Pub. Date:
All of the breadth and depth of organic drug synthesis-in one resource
This work offers a clear examination of the synthetic routes followed to prepare a range of compounds with assigned generic names. With drugs selected for the illustrative value of the chemistry used for synthesis, the book illustrates a great variety of organic transformations and structural classes of compounds.
Ideal for anyone learning or working in organic, medicinal, or pharmaceutical chemistry today, Strategies for Organic Drug Synthesis and Design includes:
• Coverage of carbocyclic and heterocyclic compounds-steroids, opioid analgesics, beta lactam antibiotics, and more
• Hundreds of reaction flow charts detailing routes used to prepare over 600 compounds
• Biological rationales for drug classes and actions of individual agents
• Capsule presentations of basic principles of drug action
• An extensive chemical reaction index with over 3,000 entries.
|Edition description:||Older Edition|
|Product dimensions:||6.38(w) x 9.43(h) x 1.09(d)|
About the Author
DANIEL LEDNICER has devoted his career in both the private and public sectors to the search for new therapeutic agents. A former chemist and project officer at the National Cancer Institute, he has held the positions of director of chemical research at Mead Johnson, director of pharmaceutical sciences at Adria Laboratories, and pharmaceutical manager at Analytical Biochemistry Laboratories. He is the editor of the Wiley series The Organic Chemistry of Drug Synthesis.
Table of Contents
Prostaglandins, Protease Inhibitors, and Retinoids.
Drugs Based on a Substituted Benzene Ring.
Indenes, Naphthalenes, and Other Polycyclic Aromatic Compounds.
Steroids: Part 1: Estranes, Gonanes, and Androstanes.
Steroids: Part 2: Compounds Related to Progesterone and Cortisone.
Nonsteroidal Estrogens and Their Antagonists.
Drugs Based on Five-Membered Heterocycles.
Drugs Based on Six-Membered Heterocycles.
Five-Membered Heterocycles Fused to a Benzene Ring.
Six-Membered Heterocycles Fused to a Benzene Ring.
Seven-Membered Heterocyclic Rings Fused to Benzene.
Heterocycles Fused to Two Benzene Rings.
Heterocycles Fused to Other Heterocyclic Rings.
Cross Index of Compounds.
What People are Saying About This
'In this book, Lednicer presents a detailed discussion of strategies toward the synthesis of pharmaceutical compounds. . . The strength of the book is the wealth of data collected in one relatively short tone?.