Synthetic Peptides in the Search for T and B Cell Epitopes

Synthetic Peptides in the Search for T and B Cell Epitopes

by Eva Rajnavolgyi


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Product Details

ISBN-13: 9781570591600
Publisher: Taylor & Francis
Publication date: 12/28/1994
Series: Molecular Biology Intelligence Unit Series
Pages: 200
Product dimensions: 6.50(w) x 1.50(h) x 9.50(d)

Table of Contents

2How Do B and T Cells See Antigen?3
3Prediction of B- and T-Cell Epitopes19
4Novel Approaches in Peptide Synthesis31
4.1Chemical Peptide Synthesis31
4.2Peptide Libraries Displayed on Bacteriophages53
5Conformation of B- and T-Cell Epitopic Peptides67
6Synthetic Peptide Constructs to Increase the Immunogenicity of B-Cell Epitopes97
7Synthetic Peptides as T-Cell Epitopes119
7.1An Alternative View for the Topographical Orientation of the T-Cell Receptor to the MHC-Antigen Complex119
7.2Antigen Processing Pathways141
8B- and T-Cell Epitope Analysis in Infectious Diseases155
8.1B-Cell Epitopes in Herpes Simplex Virus-1 (HSV-1) Glycoprotein D (gD)157
8.2T-Cell Epitopes in Herpes Simplex Virus (HSV-1) Glycoprotein D (gD)169
8.3Functional Relevance of B- and T-Cell Epitopes in the Conserved Intersubunit Region of Influenza Virus Hemagglutinin173
9Epitope Mapping in Cancer Research: Probing Paratopes with Cancer Epitopes193

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