Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

by Robert G. Lahita (Editor)
Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

by Robert G. Lahita (Editor)

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Overview

Systemic Lupus Erythematosus, Fourth Edition, provides an understanding of the basic mechanisms as well as the diagnostic and therapeutic aspects of lupus. This book is attractive to both the investigative community and clinicians. As lupus has become a paradigm for the study of autoimmune disease, immunologists investigating autoimmunity are becoming more interested in lupus. Basic immunology of phospholipid antibodies, clotting abnormailities, issues concerning pathogenetic fit with SLE, and newest methods of therapy of APLS are given in this newest edition of a classic reference.
  • Comprehensive current coverage of basic models of etiology and pathogenesis
  • Complete catalog of autoantibodies produced
  • Includes an outstanding review of imaging techniques for the diagnosis of lupus and its complications for each organ system
  • Includes CD-ROM of images excellent for teaching purposes and downloading into presentations

Product Details

ISBN-13: 9780080474540
Publisher: Elsevier Science
Publication date: 06/09/2004
Sold by: Barnes & Noble
Format: eBook
Pages: 1343
File size: 40 MB
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About the Author

Dr. Robert Lahita is Clinical Professor of Medicine at Rutgers University, and the Director of the Institute for Autoimmune and Rheumatic Diseases. He is a fellow of the ACP and the Royal College, and a master of the ACR. Dr. Lahita is the author of more than 16 books and 150 scientific publications in the field of autoimmunity. He is the editor of the standard textbook Systemic Lupus Erythematosus and the Senior Editor of the Textbook of Autoimmunity, and the author of Lupus: Q and A for patients and Autoimmunity in Women.

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No other Lupus text provides such an amalgam of basic research and clinical practice of the highest caliber

Table of Contents

Foreword
Introduction to 4th Edition
Pathogenesis
Autoimmunity and Autoimmune Diseases like Systemic Lupus Erythematosus
Overview of Cellular Immune Function in Systemic Lupus Erythematosus
Etiopathogenesis of Systemic Lupus Erythematosus: The Itineraries of Three Troikas
MHC Class II and Non-MHC Genes in the Pathogenesis of Systemic Lupus Erythematosus
Genetic Susceptibility and Class III Complement Genes
Complement Deficiency and Systemic Lupus Erythematosus
Gender and Age in Systemic Lupus Erythematosus
Animal Models
Genes and Genetics of Murine Systemic Lupus Erythematosus
Systemic Lupus Erythematosus in Domestic Animals

Autoantibodies and Antigens
Anti-DNA Antibodies : Structure, Assembly and Diversity
Antibodies to Cytoplasmic Antigens
Antihistone Antibodies
Antibodies to Non-Histone Agents in Systemic Lupus Erythematosus
Immune Complexes
Origins of Antinuclear Antibodies

Clinical Approach to Diagnosis
The Clinical Presentation of Systemic Lupus Erythematosus
Neonatal Systemic Lupus Erythematosus Syndromes
Systemic Lupus Erythematosus in Childhood
Imaging of Systemic Lupus Erythematosus: State of the Art
Monitoring Patients and Systemic Lupus Erythematosus
Laboratory Evaluation of Patients with Systemic Lupus Erythematosus
Systemic Lupus Erythematosus Pregnancy
Epidemiology of Systemic Lupus Erythematosus
Overlap Syndromes: Mixed Connective Tissue Disease and Sjögren's Syndrome
Systemic Lupus Erythematosus and Fibromyalgia

Organs Affected by Systemic Lupus Erythematosus
Nervous system:
Central Nervous System Systemic Lupus Erythematosus
Psychiatric Aspects of Systemic Lupus Erythematosus
Cognitive Dysfunction in Systemic Lupus Erythematosus
Dermatology:
Systemic Lupus Erythematosus and the Skin
Renal:
Systemic Lupus Erythematosus and the Kidney
Cardiopulmonary:
Cardiovascular Systemic Lupus Erythematosus
Systemic Lupus Erythematosus and the Cardiovascular System: Vasculitis
Systemic Lupus Erythematosus and the Lung
Gastrointestinal:
Nonhepatic Gastrointestinal Manifestations of Systemic Lupus Erythematosus
Hepatic Disease and Systemic Lupus Erythematosus: Coincidence or Converence
Hematology:
The Cellular Hematology of Systemic Lupus Erythematosus
Musculoskeletal:
Articular Manifestations of Systemic Lupus Erythematosus
Osteoporosis and Metabolic Bone Disease in Systemic Lupus Erythematosus

Specific Syndromes
Phospholipid Syndrome:
Immunology of Antiphospholipid Antibodies and Co-factors
The Clinical Aspects of the Antiphospholipid Syndrome
The Catastrophic Phospholipid Syndrome
Hematology: Coagulation Problems
The Antiphospholipid Syndrome: Pathogenesis and Implications for Systemic Lupus Erythematosus
Drug Induced Systemic Lupus Erythematosus:
Pathophysiology of Drug-Induced Systemic Lupus Erythematosus
Drug and Environmental Systemic Lupus Erythematosus: Clinical Manifestations and Differences
Therapy of Systemic Lupus Erythematosus
Corticosteroid Use in Systemic Lupus Erythematosus
Antimalarials and Immunosuppresive Therapies
Unproven and Experimental Therapies

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