Tailored Polymer Architectures for Pharmaceutical and Biomedical Applications

Tailored Polymer Architectures for Pharmaceutical and Biomedical Applications

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Product Details

ISBN-13: 9780841227989
Publisher: American Chemical Society
Publication date: 11/22/2013
Series: ACS Symposium Series , #1135
Pages: 376
Product dimensions: 6.20(w) x 9.00(h) x 1.10(d)

About the Author

Carmen Scholz is Professor of Chemistry at the University of Alabama in Huntsville. Jorg Kressler is Professor of Physical Chemistry at The Martin Luther University Halle-Wittenberg.

Table of Contents

Preface .............................................................................................................................. xi
Introduction
1. Introduction to Polymers in Today's Biomedical Realm ...................................... 3
Carmen Scholz and Jörg Kressler
Polymers with New Designs
2. Polyether-Based Lipids Synthesized with an Epoxide Construction Kit:
Multivalent Architectures for Functional Liposomes ......................................... 11
Sophie S. Müller, Carsten Dingels, Anna Maria Hofmann, and Holger Frey
3. Bioactive-Based Poly(anhydride-esters) and Blends for Controlled Drug
Delivery ................................................................................................................... 27
R. Fogaça, M. A. Ouimet, L. H. Catalani, and K. E. Uhrich
4. Fatty Acid Modified Poly(glycerol adipate) - Polymeric Analogues of
Glycerides ............................................................................................................... 39
T. Naolou, V. M. Weiss, D. Conrad, K. Busse, K. Mäder, and J. Kressler
5. Poly(oxazoline) Block Copolymers for Biomedical Applications ...................... 53
Michael J. Isaacman and Luke Theogarajan
6. Investigating the Secondary Structure of Oligomeric Poly(amino acid)s ......... 69
David Ulkoski, Tracy Armstrong, and Carmen Scholz
7. Polymeric Micelles Stabilized by Electrostatic Interactions for Drug
Delivery ................................................................................................................... 87
Yuichi Ohya
Modern Therapies
8. Combating HIV-1 Entry and Fusion with Peptide-Synthetic Polymer
Conjugates ............................................................................................................ 105
Maarten Danial and Harm-Anton Klok
9. Cancer Stem Cells: Potential Target For Anti-Cancer Nanomedicines ......... 127
Yan Zhou, Jiyuan Yang, and Jindrich Kopecek
10. Enhanced Delivery of Polymer Therapeutics to Solid Tumors ........................ 151
Adam J. Gormley, Nate Larson, and Hamidreza Ghandehari
Delivery of Biomacromolecules
11. Fine-Tuning of Repeating Aminoethyelene Units in Poly(aspartamide) Side
Chains for Enhanced siRNA Delivery ................................................................ 189
Kanjiro Miyata, R. James Christie, Tomoya Suma, Hiroyasu Takemoto,
Hirokuni Uchida, Nobuhiro Nishiyama, and Kazunori Kataoka
12. Dendrimer-Based RNA Interference Delivery for Cancer Therapy ............... 197
Leyuan Xu, W. Andrew Yeudall, and Hu Yang
13. Challenges for PEGylated Proteins and Alternative Half-Life Extension
Technologies Based on Biodegradable Polymers .............................................. 215
Ahmed Besheer, Robert Liebner, Martin Meyer, and Gerhard Winter
14. Thermoresponsive Polymers with Functional Groups Selected for
Pharmaceutical and Biomedical Applications ................................................... 235
Naohiko Shimada and Atsushi Maruyama
Tissue Engineering
15. Biomaterial-Induced Angiogenesis To Address Peripheral Vascular Disease:
The Application of Sphere Templated Hydrogels ............................................. 245
Dale Terasaki, Michael Sobel, Colleen Irvin, Errol Wijelath, and Buddy D. Ratner
16. Novel Cellulose Derivatives with Mitogenic and Osteogenic Activity ............. 259
Kai Zhang, Dieter Peschel, Steffen Fischer, and Thomas Groth
17. Tailoring Silk-Based Matrices for Tissue Regeneration ................................... 281
A. Motta, C. Foss, and C. Migliaresi
Surfaces and Sensors
18. Health and Safety via Surface Modification of Polyurethanes ........................ 303
Kenneth J. Wynne, Pinar Kurt, Kennard Brunson, Asima Chakravorty, Murari Gupta,
Wei Zhang, Lynn Wood, and Dennis E. Ohman
19. Antimicrobial Polymers: Molecular Design as Synthetic Mimics of
Host-Defense Peptides .......................................................................................... 319
Edmund F. Palermo, Satyavani Vemparala, and Kenichi Kuroda
20. Discrimination of Influenza Virus Strains and Super High Sensitive
Detection of Viruses Using Sugar Chip and Sugar-Chain Immobilized Gold
Nanoparticles ........................................................................................................ 331
Yasuo Suda, Xu Zhang, Yuko Takahashi, Risa Yokoyama, Mami Nagatomo,
Kazue Aoyama, Toshiomi Okuno, Shigeru Saito, Saeko Morikawa, Satoshi Hiroi,
Tetsuo Kase, Naoki Murakami, Junichiro Nishi, and Masahiro Wakao
Editors' Biographies .................................................................................................... 351
Indexes
Author Index ................................................................................................................ 355
Subject Index ................................................................................................................ 357

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