What is the physiological, pharmacological, nutritional, and pathological role of taurine? This latest volume in our mini series of Taurine Symposia proceedings, Taurine - Significance for the 21st Century, held September 20-23, 2002, in Kauai, Hawaii, discusses the role and actions of taurine and attempts to answer this central question.
Table of ContentsA Voice From the Past; J. Sturman. Dr Ralph Dawson Jr. (1954-2002).
1: Cardiovascular and Renal Effects of Taurine. 1. Inhibitory Mechanism of Taurine on the Platelet-Derived Growth Factor BB-Mediated Proliferation in Aortic Vascular Smooth Muscle Cells; K. Imada, et al. 2. Taurine on Sino-Atrial Nodal Cells: Ca2+-Dependent Modulation; H. Satoh. 3. Cellular Characterization of Taurine Transporter in Cultured Cardiac Myocytes and Nonmyocytes; T. Takatani, et al. 4. Taurine Transporter in Cultured Neonatal Cardiomyocytes: a Response to Cardiac Hypertrophy; T. Itoh, et al. 5. Effects of Taurine and Coenzyme Q10 in Patients with Acute Myocardial Infarction; R.B. Singh, et al. 2 Additional Articles.
2: Role of Taurine in Diabetes. 8. Taurine Reduces Mortality in Diabetic Rats: Taurine and Experimental Diabetes Mellitus; F. Franconi, et al. 9. The Effect of Dietary Taurine Supplementation on Plasma and Urinary Free Amino Acid Concentrations in Diabetic Rats; Young-Mi Lee, et al. 10. Insulin-Stimulated Taurine Uptake in the Rat Retina; R. Salceda. 11. The Effects of Taurine Supplementation on Patients with Type 2 Diabetes Mellitus; K.B. Chauncey, et al. 12. Hypoglycemic Effects of Taurine in the Alloxan-Treated Rabbit: a Model for Type 1 Diabetes; T.E. Tenner Jr., et al.
3: Osmoregulatory Properties of Taurine and Taurine Transport. 13. Taurine and Cellular Volume Regulation in the Hippocampus; J.E. Olson, et al. 14. Regulation of the Volume-Sensitive Taurine Efflux Pathway in NIH3T3 Mouse Fibroblasts; I.H. Lambert. 15. Taurine Counteracts Cell Swelling in Rat Cerebrocortical Slices Exposed to Ammonia in Vitro and in Vivo; R.O. Law, et al. 16. Cloning of Human Intestinal Taurine Transporter and Production of Polyclonal Antibody; Hye Suk An, et al. 10 Additional Articles.
4: Taurine Synthesis, Localization. Determination, and Nutrition. 27. Determination of Taurine and Hypotaurine in Animal Tissues by Reversed-Phase High-Performance Liquid Chromatography after Derivization with Dabsyl Chloride; H. Nakamura, T. Ubuka. 28. Immunohistochemical Localization of Taurine in the Rat Stomach; Ning Ma, et al. 29. Modulation of Taurine on CYP3A4 Induction by Rifampicin in a HepG2 Cell Line; K. Takahashi, et al. 30. Effect of Acute Ethanol Administration on S-Amino Acid Metabolism: Increased Utilization of Cysteine for Synthesis of Taurine Rather than Glutathione; Young S. Jung, et al. 31. Effects of Dietary Taurine Supplementation on Hepatic Morphological Changes of Rats in Diethynitrosamine-Induced Hepatocarcinogenesis; Kyung Ja Chang, et al. 6 Additional Articles.
5: Taurine: Growth, Antioxidants, and Inflammation. 38. Why is Taurine Cytoprotective? S. Schaffer, et al. 39. Taurine, Analogues and Bone: a Growing Relationship; R.C. Gupta, Sung-Jin Kim. 40. Anti-Inflammatory Activities of Taurine Chloramine: Implication for Immunoregulation and Pathogenesis of Rheumatoid Arthritis; E. Kontny, et al. 41. Taurine Chloramine Inhibits Production of Inflammatory Mediators and iNOS Gene Expression in Alveolar Macrophages: a Tale of Two Pathways: Part I: NF-kappa B Signaling; M.R. Quinn, et al. 42. Taurine Chloramine Inhibits Production of Inflammatory Mediators and iNOS Gene Expression in Alveolar Macrophages: a Tal