ISBN-10:
3642099343
ISBN-13:
9783642099342
Pub. Date:
11/29/2010
Publisher:
Springer Berlin Heidelberg
Telepathology / Edition 1

Telepathology / Edition 1

by Sajeesh Kumar, Bruce E. Dunn
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Overview

Written by experts from around the globe, Telepathology explains technical issues, digital information processing and collective experiences from practitioners in different parts of the world practicing a wide range of telepathology applications. This includes telepathology for gastrointestinal biopsy specimens, telepathology at the United States Veterans Health Administration, experience with teleneuropathology, applications of virtual microscopy, telepathology in micrographic surgery, dynamic and static robotic techniques for real-time telepathology, telecytology, feasibility and diagnostic agreement in teledermatopathology, remote control of the scanning electron microscope, ultrastructural telepathology, remote EM diagnostics and telepathology for rapid diagnosis of neurosurgical specimens. The authors lay the foundation for the globalization of telepathological procedures based on the idea that a pathological analysis can be performed on a patient anywhere in the world.

Product Details

ISBN-13: 9783642099342
Publisher: Springer Berlin Heidelberg
Publication date: 11/29/2010
Edition description: Softcover reprint of hardcover 1st ed. 2009
Pages: 238
Product dimensions: 6.10(w) x 9.25(h) x 0.24(d)

Table of Contents

Chapter 1 Introduction to Telepathology Sajeesh Kumar 1

1.1 Introduction to Telemedicine 1

1.2 What Is Telepathology? 1

1.3 Scope of Telepathology 2

1.4 Relevance of Telepathology in Developing Countries 3

1.5 Summary 4

Chapter 2 Digital Slide and Virtual Microscopy-Based Routine and Telepathology Evaluation of Gastrointestinal Biopsy Specimen Bela Molnar Lajos Berczi Levente Ficsor Viktor Varga Attila Tagscherer Zsolt Tulassay 5

2.1 Introduction 5

2.2 Materials and Methods 6

2.2.1 Gastric Routine Biopsy Specimen Analysis 6

2.2.2 Data Analysis 8

2.2.3 Slide Digitization and the VM System 9

2.2.3.1 Use Hardware Tools 9

2.2.3.2 Features of the Digital Slide Scanning Program 10

2.2.3.3 Features of the VM Program 10

2.3 Results 13

2.3.1 Concordance 13

2.3.2 Reasons for Diagnostic Discordance 13

2.3.3 Technical and Practical Data at the Application of VM 14

2.4 Discussion 15

2.5 Summary 16

References 17

Chapter 3 Telepathology as an Essential Networking Tool in VISN 12 of the United States Veterans Health Administration Bruce E. Dunn Hongyung Choi Daniel L. Recla Thomas R. Wisniewski 19

3.1 Background 19

3.2 Primary Diagnosis and Clinical Consultation in Surgical Pathology 21

3.3 Diagnosis and Consultation in Clinical Pathology 25

3.4 Future Developments in Telepathology 26

3.5 Summary 28

Acknowledgment 28

References 29

Chapter 4 Teleneuropathology Georg Hutarew 31

4.1 Available Systems 31

4.1.1 Light Microscopes 31

4.1.2 Scanner Systems 32

4.1.3 Robotic Microscopes 32

4.1.4 Systems Similar to Microscopes 32

4.2 Intraoperative Frozen Section Diagnosis 32

4.2.1 General 32

4.2.2 Equipment for Frozen Section Diagnosis33

4.2.2.1 Gross Examination 33

4.2.2.2 Microscope 33

4.2.2.3 Telepathology Software 35

4.2.2.4 Diagnosis 36

4.2.2.5 Laboratory Equipment 36

4.2.3 Sequence of Frozen Sections 39

4.2.4 Statistical Evaluation 2000-2007 41

4.3 Second-Opinion Diagnosis and Specialist Discussion 43

4.3.1 Digital Camera 44

4.3.2 Video Camera 44

4.3.3 Robotic Microscope 44

4.4 Database with Virtual Slides 45

4.5 Data Protection 45

4.6 Discussion of Teleneuropathology 45

4.7 Future Aspects 47

4.8 Summary 48

Appendix Situation in Austria 48

Acknowledgments 49

References 50

Chapter 5 Applications of Virtual Microscopy P.H.J. Riegman W.N.M. Dinjens M.H.A. Oomen W.F. Clotscher R.J.J.R. Scholte W. Sjoerdsma A.R.A. Riegman J.W. Oosterhuis 53

5.1 Introduction 53

5.2 Steady Replacement of Microscopes 53

5.3 Education 54

5.4 Ring Trials 55

5.5 Pilot for Implementation in Routine Pathology 56

5.6 Privacy-Sensitive Network Environment 57

5.7 External Applications 58

5.7.1 Tissue Banking 58

5.7.2 Multicenter Trials 59

5.7.3 Tissue Microarray Analysis 59

5.7.4 Histopathology Forum 59

5.8 Future Developments 60

5.9 Summary 61

Acknowledgments 62

References 63

Chapter 6 Telepathology in Veterinary Diagnostic Cytology Paola Maiolino Gionata de Vico 63

6.1 Background Information 63

6.2 Human and Veterinary Global Experience 64

6.3 Guidelines for Preparation of Telecytologic Cases 65

6.4 Limitations and Future Directions 66

6.5 Education and Training Opportunities Available 67

6.6 Summary 68

References 69

Chapter 7 Use of Telepathology in Mohs Micrographic Surgery Julie K. Karen Klaus J. Busam Kishwer S. Nehal 71

7.1 Background 71

7.1.1 Mohs Micrographic Surgery 71

7.1.2 Telepathology 72

7.2 Telepathology in Dermatology 72

7.3 Telepathology in Mohs Micrographic Surgery 73

7.3.1 Feasibility 73

7.3.2 Clinical Experience 74

7.3.3 Limitations 76

7.4 Future Directions 76

7.5 Summary 77

References 78

Chapter 8 Combining Dynamic- and Static-Robotic Techniques for Real-Time Telepathology Vincenzo Della Mea Palmina Cataldi Barbara Pertoldi Carlo A. Beltrami 79

8.1 Introduction 79

8.2 Methods 80

8.2.1 The Cases 81

8.2.2 The Telepathology System 81

8.2.3 Statistical Analysis 82

8.3 Results 83

8.3.1 The Diagnoses 83

8.3.2 The Time 83

8.3.3 The Static Images 84

8.4 Discussion 86

8.5 Summary 87

Acknowledgment 87

References 88

Chapter 9 Telepathology in Iran Afshin Abdirad Siavash Ghaderi-Sohi 91

9.1 Telepathology in Middle East 92

9.2 Telepathology in Iran 93

9.2.1 Teleconsultation in Iran 93

9.2.2 Remote Primary Diagnosis in Iran 95

9.2.3 Remote Education in Iran 95

9.2.4 Quality Assurance Programs in Iran 97

9.3 Problems 97

9.4 What Have Been Done? 98

9.5 Summary 101

References 101

Chapter 10 Telepathology in Japan Takashi Sawai 105

10.1 The Present Conditions of Japanese Diagnostic Pathology and the Background of Development of Telepathology 105

10.2 The History of IT and Telepathology in Japan 110

10.3 Recent Governmental Policy and Activity to Telepathology 111

10.4 The Purpose of Japanese Telepathology, Especially Intraoperative Rapid Diagnosis 113

10.5 Development of Infrastructure and Telepathology Systems in Japan 116

10.6 Telepathology Applications in Medical Field 118

10.7 The Telepathology System in Future 121

10.7.1 The Government Strategy to Telepathology 121

10.7.2 Technological Development of DVDs and the Imaging Compression Technology 123

10.8 Problems Relating the Prevalence of Telepathology in Japan 123

10.9 Summary 124

References 125

Chapter 11 Telepathology in Hungary M. Cserneky B. Szende L. Fonyad T. Krenacs 127

11.1 Historical Background 127

11.2 First Steps to Introduce Telepathology in Hungary 129

11.3 Further Developments Supported by the European Union 130

11.4 Structure and Function of Bepro in Hungary 131

11.4.1 General Considerations 131

11.4.2 Structure of the Telepathology Stations 132

11.4.3 Function of the Bepro Project Between November 2001 and June 2002 132

11.4.4 Main Results of the Bepro Project 135

11.5 The Era of Digital Slides in Hungary 135

11.5.1 The Potential of Digital Slides in Histopathology 135

11.5.2 Pilot Studies for Telepathology Using Digital Slides 137

11.6 Present and Future of Dynamic Telepathology in Hungary 138

11.6.1 Digital Microscopy for Teaching Histopathology in Hungary 140

11.6.1.1 E-Learning 140

11.6.2 Digital Microscopy for Gradual Teaching 141

11.6.3 Digital Microscopy for Postgradual Teaching, EQA, and E-Learning 142

11.7 Video Conference Services for the Hungarian Higher-Education and Research Community 143

11.8 Conclusion 145

11.9 Summary 145

References 146

Chapter 12 Telecytology: A Retrospect and Prospect Aruna Prayaga 149

12.1 Background Information 149

12.2 Global Experience 152

12.3 Future Perspective 155

12.3.1 Indian Scenario 158

12.4 Education and Training Opportunities Available 159

12.5 Summary 160

Acknowledgments 160

References 161

Chapter 13 Teledermatopathology: Current Status and Perspectives Cesare Massone Alexandra Maria Giovanna Brunasso H. Peter Soyer 163

13.1 Introduction 163

13.2 SAF Teledermatopathology 164

13.3 Real-Time (Dynamic) Teledermatopathology 168

13.4 Virtual Microscope Teledermatopathology 169

13.5 Conclusions 176

13.6 Summary 176

References 177

Chapter 14 Ultrastructural Telepathology: Remote EM Diagnostic via Internet Josef A. Schroeder 179

14.1 Introduction 179

14.2 The Digital Era 182

14.3 From Remote to Virtual Light Microscopy 182

14.4 Implications for Diagnostic Electron Microscopy 183

14.5 The Need for Ultrastructural Telepathology 185

14.6 Remote Electron Microscopy 186

14.7 The Ultrastructural Telepathology Setup 186

14.8 Extension of the Server-Client Architecture 189

14.9 Performance of the Ultrastructural Telepathology 192

14.10 Illustrative Telepathology Diagnostic and Basic Research Examples 194

14.11 Discussion and Conclusions 196

14.12 Summary 198

Acknowledgements 199

References 199

Chapter 15 Remote Control of the Scanning Electron Microscope Atsushi Yamada 205

15.1 Scanning Electron Microscope 205

15.1.1 Principle 205

15.1.2 Treatment of Biological Sample 205

15.1.3 Observation 206

15.2 Remote Control of the SEM 207

15.2.1 Effectiveness of the Remote Control 207

15.2.2 Conditions Required For Remote Control 207

15.3 Practical Use of Remote Control Lock System 208

15.3.1 System Using a Web Browser 208

15.3.1.1 Construction 209

15.3.1.2 Communication Method 209

15.3.2 Remote Desktop System 213

15.3.2.1 Construction 213

15.3.2.2 Communicaiton Method 214

15.4 Data Transfer and Response 214

15.4.1 Amount of Data Transfer 215

15.4.1.1 WEB-SEM 215

15.4.1.2 Remote Desktop 215

15.4.2 Technique for Improving a Response 216

15.4.2.1 Reduction of a Communication Amount of Data 217

15.4.2.2 Single-Action Operation 217

15.4.3 Case of the Operation of Remote Control 218

15.4.3.1 Difference in a Communication Method 218

15.4.3.2 Communication Channel and a Response 220

15.4.3.3 Communication and a Remote Control System 222

15.5 Conclusion 223

Summary 224

Chapter 16 Telepathology: An Audit Sajeesh Kumar 225

16.1 Telepathology is Advancing 225

16.2 Will Telepathology Replace Traditional Methods? 225

16.3 Issues Related to Telepathology: A Brief Overview 226

16.4 Changing Industry 226

16.5 Technical Challenge 227

16.6 Money Matters 227

16.7 Conclusion 228

Glossary 229

Subject Index 237

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