Testicular Cell Dynamics Vol 1061 / Edition 1 available in Paperback
- Pub. Date:
The past few years have brought an influx of new information intothe field of male reproduction. Several laboratories have been ableto apply the genomics approach to gene expression in the male,revealing previously unknown patterns of gene expression and geneproducts that were localized in male reproductive tract tissues andcells for the first time. These discoveries paved the way for thenext wave, an opportunity to analyze male reproductive biology andthe processes by which sperm are formed in the seminiferous tubuleand androgen is synthesized in the interstitium of the testis.
The different levels of organization in the testis, includingthe stages of spermatogenesis, enzymatic steps of steroidogenesis,and the intracellular signaling pathways of hormones, are now moreamenable to study and selection of potential targets for drugdevelopment. This volume capitalizes on these developments with acollection of reports that is uniquely suited to stimulate researchand development ideas.
NOTE: Annals volumes are available for sale asindividual books or as a journal. For information on institutionaljournal subscriptions, please visit www.blackwellpublishing.com/nyas.
ACADEMY MEMBERS: Please contact the New York Academyof Sciences directly to place your order (www.nyas.org).Members of the New York Academy of Science receive full-text accessto the Annals online and discounts on print volumes. Please visithttp://www.nyas.org/MemberCenter/Join.aspxfor more information about becoming a member.
Table of Contents
Preface: Matt Hardy and Mike Griswold.
Part I: Development.
1. Hormonal Regulation of Male Reproductive Tract Development.(Sunita Verma-Kurvari, Serge Nef, and Luis F. Parada).
2. Sox9 in Testis Determination. (Akio Kobayashi, Hao Chang,Marie-Christine Chaboissier, Andreas Schedl, and Richard R.Behringer).
3. Seminiferous Cord Formation and Germ-Cell Programming:Epigenetic Transgenerational Actions of Endocrine Disruptors.(Michael K. Skinner and Matthew D. Anway).
4. In Vitro Generation of Germ Cells: New Techniques to SolveCurrent Issues. (Joshua M. Baughman and Niels Geijsen).
Part II: The Endocrine Axis.
5. Structure-Function Relationships of the Luteinizing HormoneReceptor. (David Puett, Yongsheng Li, Krassimira Angelova, GenevaDemars, Thomas P. Meehan, Francesca Fanelli, and PremaNarayan).
6. Transgenic Rescue of SF-1-Null Mice. (Tatiana Karpova, R. R.M. Maran, Jeremy Presley, Serge P. Scherrer, Lovella Tejada, andLeslie L. Heckert).
7. Estrogens in Testis Biology. (Jayne E. Sierens, Sharon F.Sneddon, Frances Collins, Michael R. Millar, and Philippa T. K.Saunders).
8. Foxa1 and Foxa2 Interact with the Androgen Receptor toRegulate Prostate and Epididymal Genes Differentially. (Xiuping Yu,Aparna Gupta, Yongqing Wang, Kichiya Suzuki, Janni Mirosevich,Marie-Claire Orgebin-Crist, and Robert J. Matusik).
9. Role of Glial Cell Line-Derived Neurotrophic Factor inGerm-Line Stem Cell Fate. (Laura Braydich-Stolle, Courtney Nolan,Martin Dym, and Marie-Claude Hofmann).
Part III: Steroidogenesis.
10. P450 Oxidoreductase Deficiency: A New Disorder ofSteroidogenesis. (Walter L. Miller, Ningwu Huang, Amit V. Pandey,Christa E. Flück, and Vishal Agrawal).
11. Neuroendocrine Regulation of Leydig Cell Development. (P. J.O'shaughnessy, P. J. Baker, and H. Johnston).
12. Mitochondrial Function in Leydig Cell Steroidogenesis. (DaleB. Hales, John A. Allen, Tristan Shankara, Paul Janus, Steve Buck,Thorsten Diemer, and Karen Held Hales).
13. Determining Structure and Function of Steroid DehydrogenaseEnzymes by Sequence Analysis, Homology Modeling, and RationalMutational Analysis. (William L. Duax, James Thomas, VladimirPletnev, Anthony Addlagatta, Robert Huether, Lukas Habegger, andCharles M. Weeks).
Part IV: Spermatogenesis.
14. Postnatal and Pubertal Development of the Rhesus Monkey(Macaca mulatta) Testis. (Tony M. Plant, Suresh Ramaswamy, DavidSimorangkir, and Gary R. Marshall).
15. The mRNA Encoding CstF-64 Is Expressed Ubiquitously in MouseTissues. (Zane Huber, Roberto R. Monarez, Brinda Dass, and ClintonC. MacDonald).
16. Drivers of Germ Cell Maturation. (K. L. Loveland, C.Hogarth, S. Mendis, A. Efthymiadis, J. Ly, C. Itman, S. Meachem, C.W. Brown, and D. A. Jans).
17. Role of Nuclear Receptors in INSL3 Gene Transcription inLeydig Cells. (Jacques J. Tremblay and Nicholas M. Robert).
18. Analysis of the Human Sperm Proteome. (Daniel S. Johnston,Joe Wooters, Gregory S. Kopf, Yongchang Qiu, and Kenneth P.Roberts).
Part V: Clinical Correlates.
19. Male Gamete Contributions to the Embryo. (RyuzoYanagimachi).
20. The Androgen Microenvironment of the Human Testis andHormonal Control of Spermatogenesis. (Jonathan P. Jarow and BarryR. Zirkin).
21. Sperm Chemotaxis: A Primer. (E. Hildebrand and U. B.Kaupp).
22. Epigenetic Regulation of Testis-Specific Gene Expression.(John R. McCarrey, Christopher B. Geyer, and HirotakaYoshioka).
Index of Contributors.