The Cobra Event
“One of those books you literally can’t put down . . . makes The Hot Zone virus—far away in a rainforest—look like no big deal.”—Detroit Free Press

Five days ago, a homeless man on a subway platform died in agony as startled commuters looked on. Yesterday, a teenager started having violent, uncontrollable spasms in art class. Within minutes, she too was dead.

Dr. Alice Austen is a medical pathologist at the Centers for Disease Control in Atlanta. What she knows is that the two deaths are connected. What she fears is that they are only the beginning. . . .

“Manages to grab you with the authenticity of its scientific detective work and haunt you with its sheer plausibility.”—Entertainment Weekly
1100621309
The Cobra Event
“One of those books you literally can’t put down . . . makes The Hot Zone virus—far away in a rainforest—look like no big deal.”—Detroit Free Press

Five days ago, a homeless man on a subway platform died in agony as startled commuters looked on. Yesterday, a teenager started having violent, uncontrollable spasms in art class. Within minutes, she too was dead.

Dr. Alice Austen is a medical pathologist at the Centers for Disease Control in Atlanta. What she knows is that the two deaths are connected. What she fears is that they are only the beginning. . . .

“Manages to grab you with the authenticity of its scientific detective work and haunt you with its sheer plausibility.”—Entertainment Weekly
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The Cobra Event

The Cobra Event

by Richard Preston
The Cobra Event

The Cobra Event

by Richard Preston

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Overview

“One of those books you literally can’t put down . . . makes The Hot Zone virus—far away in a rainforest—look like no big deal.”—Detroit Free Press

Five days ago, a homeless man on a subway platform died in agony as startled commuters looked on. Yesterday, a teenager started having violent, uncontrollable spasms in art class. Within minutes, she too was dead.

Dr. Alice Austen is a medical pathologist at the Centers for Disease Control in Atlanta. What she knows is that the two deaths are connected. What she fears is that they are only the beginning. . . .

“Manages to grab you with the authenticity of its scientific detective work and haunt you with its sheer plausibility.”—Entertainment Weekly

Product Details

ISBN-13: 9780345409973
Publisher: Random House Publishing Group
Publication date: 08/29/1998
Edition description: Reprint
Pages: 448
Sales rank: 114,964
Product dimensions: 4.10(w) x 6.80(h) x 1.10(d)
Lexile: 840L (what's this?)
Age Range: 14 - 18 Years

About the Author

About The Author
Richard Preston is the author of three nonfiction books, The Hot Zone (about the Ebola virus), American Steel (about a revolutionary steel mill), and First Light (about modern astronomy). He is a contributor to The New Yorker and has won numerous awards, including the McDermott Award in the Arts from MIT, the American Institute of Physics Award in science writing, and the Overseas Press Club of America Whitman Basso Award for best reporting in any medium on environmental issues.

The Cobra Event is Richard Preston's first novel.

Hometown:

Hopewell, New Jersey

Date of Birth:

August 5, 1954

Place of Birth:

Cambridge, Massachusetts

Education:

B.A., Pomona College, 1976; Ph.D. in English, Princeton University, 1983

Read an Excerpt

Part One

TRIAL

Arc of the Circle

NEW YORK CITY, LATE 1990S


KATE MORAN was an only child. She was seventeen years old and lived with her parents in a loft apartment on the top floor of a handsome old building to the west of Union Square, just on the edge of Greenwich Village. One Wednesday morning in late April, Kate was slow getting up. She had woken in the middle of the night in a sweat, but it went away, and she fell back asleep, into bad dreams that she could not remember. She came awake with a fresh cold, and she could feel her period coming on.

"Kate!" It was Nanette, the housekeeper, calling to her from the kitchen. "Katie!"

"Okay." She didn't like being called Katie. She sat up and found a Kleenex and blew her nose, and went into the bathroom. She brushed her teeth, then went back into the bedroom and dressed in a flowered dress that she had found in a flea market. The mornings could be chilly this time of year, so she put on a sweater. Kate had wavy russet hair, beautiful hair with natural pale highlights, which she wore medium length. Her eyes were grayish blue or bluish gray, depending on the light and the weather and her mood (or so she liked to think); complicated eyes. Her face was changing fast. She could almost see the bones of the woman emerging, yet she had found that the more she stared at her face in a mirror the less she understood it. She thought about this as she brushed her hair, pushing it back so that the two platinum earrings in her left ear were visible.

Kate's mother called her the Packrat, because she accumulated things. The worktable in the corner of her room was littered with old cigar boxes covered with their original illustrations, plastic boxes, metal containers, purses, bags, puzzles. Things that opened and closed. There was an old dollhouse that she had found in a junk shop in Brooklyn and had been taking apart, cannibalizing it for a project. She reached into the dollhouse and pulled out a prism made of glass, and the smooth white skull of a vole, with tiny yellow teeth, that she had bought at a bone shop in SoHo. She held the prism up to the light falling through the skylight of her bedroom, and just to see what it would look like, she held the vole's head behind the prism. No colors appeared; you needed direct sunlight. She stuffed the objects into her knapsack. They were going to become part of the Box that she was constructing in Mr. Talides's art room at the Mater School, a private girls' school on the Upper East Side.

"Katie!" Nanette was calling.

"Okay, okay." She sighed and threw her knapsack over her shoulder and went out into the living area—a large open space with polished wood floors and antique furniture and rugs. Her parents had both already left for work. Her father was a partner in a Wall Street investment house, and her mother was an attorney at a midtown law firm. In the kitchen, Nanette had poured orange juice and toasted a bagel. Kate shook her head. She wasn't hungry. She sneezed. Nanette tore off a paper towel and handed it to her. "Do you want to stay home?" "Uh-uh." Kate was already out the door and into the elevator.

It was a glorious morning. She hurried along Fifteenth Street to Union Square, striding on long legs, heading for the subway entrance. The ash trees in the square were threatening to break bud. Puffy white clouds drifted in a blue sky over the city, winds whipping in from the southwest, bringing a warmer day than Kate had expected. The daffodils were mostly gone and the tulips were blown and flopping their petals. Spring was beginning to give way to summer. A homeless man passed Kate going in the other direction, leaning into the warm wind as he pushed a shopping cart piled high with plastic garbage bags full of his possessions. She threaded through the stalls of the farmer's market that filled up the northern and western sides of the square, and at the subway kiosk she ran down the stairs and caught the uptown Lexington Avenue express.

The train was crowded, and Kate found herself crushed in a corner of the first car by the front window. It was where she had liked to stand when she was a girl riding with her mother and father, back when they had more time to take her places. You could look out the window and see the steel columns marching by under the car's headlights, and the track extending out into seemingly infinite darkness. Switches and branches whirled past, and if you were on an express train that caught up with a local on the adjacent track, there would be a moment when the two trains were locked together in a shuddering rush forward.

She didn't like it. The lights flashing in the tunnel made her feel sick. She turned away. Then she found herself looking at the faces in the subway car. The faces bothered her. If you look at too many faces jammed together, every face begins to look alien. People in the subway can look . . . humanoid.

The Mater School was only a few blocks from the Eighty-sixth Street subway station. Kate was still running a little late, and by the time she got to the stone parish building that housed the school, the younger girls had mostly gone inside, although some of the upper-school girls were hanging around on the steps.

"Kates, I have to tell you something." It was her friend Jennifer Ramosa. They walked in together, with Jennifer talking about something that Kate didn't follow. Kate felt strange, as if a feather had brushed across her face....

A gong rang...and there was the headmistress, Sister Anne Threader, going by.... For a moment Kate had a feeling of vertigo, as if she were staring into a black pit with no bottom, and she dropped her knapsack. It hit the floor with a smack. There was a sound of breaking glass.

"Kate? You moron. What's the matter with you?" Jennifer said.

Kate shook her head. It seemed to clear. She was going to be late for homeroom. "What's going on, Kates?" Jennifer asked. "I'm fine." She picked up her knapsack. It slushed and rattled. "Something broke. Damn, I broke my prism." She headed into class, annoyed with herself.

At about 10 o'clock in the morning, Kate went to the nurse's office and got some Tylenol. It didn't help her cold, which was getting worse and worse. It was a real sinus cold. Her mouth was hurting a lot; it felt bumpy and it stung. She was debating whether or not to go home. She decided to go to art class and leave after that. The art teacher, Peter Talides, was a balding, middle-aged painter, likable and disorganized, and his art room was a satisfying place. Students hung out there during the day and after school hours. Kate settled herself at a table in the corner of the room, near the window, where her assembled Box was taking shape. It was an ambitious construction, a kind of a house, made of pieces of dollhouses and all kinds of found objects. Kate felt dizzy and weak. She tried to work on the house but couldn't remember what she had planned to do with it. She felt as if she had never seen it before and as if some other person had built it.

"I want to go home," she said out loud.

The students looked at her. She started to stand up—she intended to go back to the nurse's office—when suddenly she felt really dizzy. "Oh, no," she said. She got part way to her feet, and found she couldn't stand. She sat down heavily on her work stool.

"What's the matter, Kates?" Jennifer asked.

There was a crash. Kate had slid off the stool and landed on the floor beside her worktable. Peter Talides came hurrying over. "Are you all right?"

"I'm sick," Kate said in a thick voice. She began to tremble. She was sitting on the floor with her legs out straight. "My mouth hurts."

Talides bent over her. "We need to get you to the nurse," he said.

She didn't answer. Her teeth were chattering and her face was flushed and feverish. Peter Talides was frightened. Kate's nose was running with clear mucus that flowed down over her lips. It was gushing out, as if she had a very bad cold. Her eyes flicked over his face without seeming to see him.

"Someone tell the nurse," he said. "Go on! Go!" To Kate he said, "Just sit still, okay?"

Kate said, "I think I'm going to throw up."

"Can you stand up?"

"No. Yes."

He helped her to her feet. "Jennifer. Prasaya. Please take Kate to the bathroom, will you?"

The two girls helped Kate out of the room and into the bathroom, while Peter Talides waited in the hallway. Kate stood in front of the sink, hanging on to it, wondering if she was going to throw up. Something moved inside her mind, as if some being that was not Kate but was Kate was in agony. There was a mirror over the sink. For a moment, she couldn't bring herself to look. Then she opened her mouth. The inside of the mouth reflected in the mirror was dotted with black blood blisters. They looked like shining ticks feeding there.

She screamed and hung on to the sink, and screamed again. She lost her balance and crumpled to her knees. Peter Talides ran into the bathroom. He found Kate Moran sitting on the floor, looking at him with glassy eyes. The clear mucus was running out of her nose and mouth, and she was weeping. She said in a thick voice, "I don't know what to do."

Kate's expression went blank. The left side of her face rippled in a series of twitches that moved in a wave. The twitches were marching jacksonian seizures. Suddenly she uttered a fierce, guttural cry. She toppled backward. Her knees straightened out and her body seized and froze hard in a clonic jerk. Her head hit the tiled floor with a crack. The stiffness lasted for a few seconds. Then her arms and legs began to tremble and jerk rhythmically. She lost control of her bladder. A puddle formed under her.

Talides tried to hold her arms still. "My God!" he cried.

Her legs lashed out in a clonus, knocking over a wastebasket, kicking Talides backward. She was very strong. Then her body began to scissor back and forth. Her teeth clicked together repeatedly. Her mouth was working. Her lips moved and rippled. Her tongue stuck out and was withdrawn again. Her eyes were half open. He thought Kate was looking at him and trying to say something to him. She moaned but no language came out.

Then her teeth sank into her lower lip, cutting through the lip, and a run of blood went down her chin and neck. She bit her lip again, hard, with ferocity, and she made a groaning animal sound. This time, the lip detached and hung down. She pulled her lip in, sucked it into her mouth, and swallowed. Now she was chewing again. Eating the inside of her mouth, chewing her lips, the insides of her cheeks. The movement of her teeth was insectile, like the feeding movements of an insect larva chewing on its food: intense, greedy, automatic—a kind of repetitive yanking at the tissues of her mouth. Her tongue suddenly protruded. It was coated with blood and bits of bloody skin. She was eating her mouth from the inside.

"She's biting herself!" he yelled. "Help!"

He got his hands around her head and tried to hold her chin steady, but he couldn't stop her teeth from gnawing. He could see her tongue curling and moving behind her teeth. He was begging for help at the top of his lungs. Jennifer was next to him, weeping, crying for help, too. The bathroom door was open, and students were standing in the hallway, looking in, stunned with fright. Most were crying. Several of them had run to call 911.

The girl's body went into a back-and-forth thrashing movement. Then she began to writhe. It was a type of writhing associated with damage to the base of the brain, the midbrain, a knot of structures at the top of the spinal cord. The movements were what is known as basal writhing.

Kate opened her mouth and a hoarse croak came out. She was lying on her back now. Her spine began to bend backward. Her body arched into the air. Her stomach lifted up higher and higher. Her teeth clacked together in a spasm. Her spine recurved impossibly far, lifting off the floor, until only the back of her head and her heels were touching the floor, her stomach raised up. Her body formed the shape of a C. Her head and heels were supporting her weight.

Her body remained poised in the air, writhing slowly, squirming, as if it were being driven by some force trying to escape from within. Her eyes opened wide. They were pure white. There were no pupils. The pupils had rolled up into the eye sockets. Her lips drew back from her teeth and she smiled, and a dark, bright liquid flowed from her nose. It was a nosebleed, a heavy epistaxis. With each heartbeat, a pulse of blood came from both nostrils. The epistaxis stained Talides's shirt and ran across the floor, where the blood tangled with the urine on the tiles and swirled down a drain in the center. She drew a rasping breath, inhaling blood—the nosebleed was pouring back down her airway now, running into her lungs. Her body was as hard as a piece of timber. Cracking sounds came from her spine.

The nosebleed died down.

The bleeding stopped. It stopped completely.

Her spine relaxed. She sank to the floor. She coughed once, lurching up blood mixed with sputum. Peter Talides was on top of her, his face to her face, crying, "Kate! Kate! Hang on!" He had taken a CPR class with the Red Cross years earlier, but he couldn't remember what to do.

Inside, deep in her mind, Kate came awake, fully aware. She heard Mr. Talides's voice begging her to hang on. There was an absolute peace, no feeling of pain, and she couldn't see anything. It was not possible to hang on. She thought: Oh. She fell away.

Interviews

On Monday, December 8th, barnesandnoble.com welcomed Richard Preston, author of THE COBRA EVENT.


Moderator: Welcome, Mr. Preston! We're glad you could join us. How are you tonight?

Richard Preston: Hi. I'm fine. No runny nose or anything.



Beverly Ridder from Bozeman, MT: Hello, Richard! I am a big fan and have COBRA right here in front of me. I want to say I think you are doing important work, and I want to know if there are any public health professionals -- do you dedicate your book to them as a means of pointing out a need for them?

Richard Preston: There are dedicated public health doctors. A lonely profession. My brother David Preston, a doctor in China, Maine, is one of my heroes.



Rashawn from sisna.com: Can you describe what a bioweapon is and how one might be used? I'll certainly get the book, but I was hoping you could shed light on the subject in person.

Richard Preston: RashawnA bioweapon is a powdered material, say freeze-dried Ebola virus particles or smallpox, released into the air through various means. The particles are absorbed into the human lung. One single particle can cause a fatal infection. The particles of an aerosol bioweapon can drift for 50 miles downwind.



Carry Bright from Oak Park, IL: How many novels had you written before THE HOT ZONE?

Richard Preston: Two nonfiction books FIRST LIGHT and AMERICAN STEEL. Now my first novel, THE COBRA EVENT, a suspense thriller about bioterror in New York City.



Joanne Shddhaz from Maryland: I read your HOT ZONE and have been paranoid ever since -- it is powerful stuff! What is the status of the Ebola virus right now?

Richard Preston: Status of Ebola virus it's still out there. Various smoldering outbreaks of Ebola have occurred in central Africa, in Ivory Coast, Congo, and Gabon. The hidden host of Ebola virus remains unknown. There have been at least two expeditions to the Central African rain forest to look, and the origin of Ebola has not been found yet.



Steve Fowler from slc: Richard! So nice to chat, I wonder not at your subject matter as much as your writing -- what is your background? Writing classes? Natural interest?

Richard Preston: Hi, Steve. My background Pomona College (CA), then Ph.D. in English lit. from Princeton University. Then I decided I didn't want to be a professor, so I became a freelance writer. I studied with John McPhee while at Princeton. He is a mentor and a friend. Also a master of nonfiction writing.



Alex Wallace, attorney from Long Beach, CA: I have read THE HOT ZONE and today's LA Times on Pres. Clinton's intention to consider first-strike use of nuke weapons against bioterrorists. Anticipating bioweapons retaliation by nuke or other force against the national homeland of the U.S. domestic terrorist means rapidly determining the identity of the user, which implicitly requires some form of terrorist "signature" or "tracing" method of identifying the perpetrator. International terrorism seeks publicity, but it seems less and less likely that terrorists will publicize their origins and purpose (as in the case of the self-published acknowledgments and warnings, in the Aum-reikio Sarin attack in Tokyo) if the risk of retaliation against their national homeland is escalated. Terrorism then changes form into nihilism and pure anarchy, destruction without given purpose, for destruction or retaliation sake. Given this hydra-headed result, is promising nuclear retaliation for terrorism a valid option or more of a Pandora's box offering an ever-increasing crescendo of random or anarchical attacks?Your thoughts on "tagging" basic chemicals or biological componentsIs this a totally irrelevant issue since these weapons tend to be "originated" in the perpetrator's laboratory and thus are unable to have precursor components tagged? Thank you!

Richard Preston: Alex, your long question centers on the mystery at the heart of THE COBRA EVENT. How to trace a bioweapon once it's released into a human population, in a city. Thus the need for a "Reachdeep" bioterror operations unit, as in COBRA EVENT. Is nuclear response appropriate? I don't know. First you have to identify who did the release. Then the political leadership has to decide whether to respond with nuclear counterattack. I would not personally want to have make that decision. The more likely scenario may be the lone terrorist (I don't want to give away ending of CE).



Amanda Price from Waterloo: I read that you conducted over 100 interviews while researching this book! That's amazing -- did you find or hear of anything unexpected?

Richard Preston: Amanda, every interview yields surprises, some incredible. One older man stunned me when he described how the U.S. military had conducted huge strategic tests of bioweapons in the Pacific Ocean. Another top source, a guy in the FBI, wanted to meet me in Union Station in Wash DC. He said, "Meet me by the McDonald's. You'll know me because I'll be wearing a black trench coat." (!) He was leader of the bioterror ops unit at Quantico. It was really fun.



Sam Gooden from Boston, MA: Will you participate in the screenwriting of THE COBRA EVENT? Is there one thing that you'll insist on maintaining in the transformation to film?

Richard Preston: Sam, I won't do the screenplay, thank heavens. Because if the movie is a disaster (as happens sometimes in Hollywood), they'll always try to blame the screenwriter! So I stand back and watch Hollywood do its thing. Hollywood is a parallel universe.



Dave Bryant from San Antonio: Can you discuss actual incidents of biological warfare that occurred in history?

Richard Preston: One of more important incidents was the Siege of Jaffa, around 1346. The besiegers catapulted dead humans over the city walls -- humans who'd died of plague. It is suspected that this warfare started the Black Death, the huge outbreak of plague in Mediterranean and N. Europe in summer of 1348. It killed off one third of the population, fast. Another important incident was deliberate use of smallpox-infected blankets given to Indians during French and Indian war. It killed off many populations of Native Americans. Bioweapons really work, and have been used in history.



Elvis from Jacksonville, FL: Hey, Richard, what do you do when you're not writing? What kind of books do you like to read? Wha are your biggest inspirations?

Richard Preston: Elvis1. Whitewater canoeing. 2. Mountain biking (I'm not very good at it). 3. Hanging out with my kids, telling them stories and stuff. 4. Reading. Last good book A WRINKLE IN TIME, by Madeleine L'Engle.



Kent S. from San Diego: Did you have models for your character Alice Austen? Also, are there actually FBI forensic teams, and have you ever been involved in government research?

Richard Preston: No model for Alice Austen. I made her up. Except I spent days and weeks hanging out with CDC officers, learning how they think and work, and those patterns wove into Alice's character. Yes, there are FBI forensic operations groups. the real one, the one that I call "reachdeep" in COBRA EVENT, is stationed at Quantico and is called the HMRU, which means Hazardous Materials Response Unit. They deal with bioterror.



Tea Miller from Hartford, CT: What exactly is the Ebola virus, and what does it do to humans? I'm anxious to read both of your books! Thanks!

Richard Preston: Ebola virus is a Level 4 virus. It causes a biological meltdown in the human body. You die in 3-7 days after infection, the virus melts your organs, causes hemorrhage, bruising, eyes fill up with blood, and the linings of the intestines can come off and are expelled. The victim "crashes and bleeds out," with blood running from any or all of the openings of the body. Ebola virus has been made into weapons. It can be freeze-dried, and it can drift in the air. This research was done in the old Soviet Union. Maybe in Russia today also.



Brian from Hoboken: If there were indeed a biological attack, would it be readily apparent as an attack or might it appear as merely an epidemic at first? Just ordered THE COBRA EVENT and am psyched to read it!

Richard Preston: Brian -- that's the idea of the Cobra Event. A bioterror event might be invisible, not obvious. The disease is unknown (genetically engineered virus) and it's worming its way around NY City like a common cold, hitting one person here, one there. Bioterror might be hard to identify. Then ... how do you stop it?



Manolo Hambly from LA: Did you come across one piece of evidence in your research that was especially persuasive in convincing you of the reality of germ warfare? Can you share the most powerful of your discoveries? Thanks!

Richard Preston: Manolo, the most convincing evidence was listening to my eyewitness sources describing what they'd seen and done in the Russian biowarfare facilities, especially in Obolensk and Koltsovo. Those places are truly scary, and my sources were really scared. Genetic engineering has clearly been a major focus of bioweapons research in Russia -- and in Iraq.



Laurel Z. from Long Island City: Why did you decide to write a nonfiction book after the success of THE HOT ZONE? Do you prefer one over the other?

Richard Preston: THE HOT ZONE is actually nonfiction true factual story. THE COBRA EVENT is a fictional suspense novel, but is based on a ton of facts and research. I like writing both kinds of book, for different reasons. With a novel, I love being able to spin a huge yarn, create scenes and characters. I also loved doing the field research for COBRA EVENT, exploring tunnels in NYC (I won't tell the ending).



H.D. from Cleveland: Have you been met with great skepticism with this book? I admit I myself wonder why, if this is for real, you didn't write a nonfiction book? Thanks.

Richard Preston: I didn't write CE as nonfiction for the following reasons--I couldn't get my top sources to go on record by name. --Thankfully no major bioterror event has yet occurred. So there was nothing to report on, no story. Initially there was a lot of skepticism. But the experts have weighed in and have been saying, "Hey, Preston's telling the truth. It's real. Bioweapons are here and they are very dangerous, and Preston got it right." That's been the reaction of the expert community.



Holly McC from West Hartford, CT: What do you recommend we do as a nation and as individuals to protect ourselves in case biological warfare should happen?

Richard Preston: What to do...1. As citizens, we should demand our government tell us what it knows about bioweapons in countries around the world. Send email to the White House. 2. Demand that the government stockpile medicines, and demand the government give us an emergency response plan. 3. Individually, educate ourselves. This is especially important for doctors and first responders. They should learn the basic symptoms of things like anthrax and smallpox...just in case. The medical people will be on the front line in any bioterror attack.



Anita Blankenship from St. Louis: Hello, Mr. Preston, I read THE HOT ZONE -- just finished it and loved it -- as soon as I heard you had another book coming. I am now about to start COBRA. Can you tell me whether our government has taken strides to protect us from the possibility of biological warfare? Do we have the technology to detect such weaponry? Thank you and good night!

Richard Preston: Yes, the government is working on biosensor machines. I've seen some stuff. There's a biosensor device used by the U.S. Navy that looks like a pregnancy strip tester. You put a liquid sample on it, and it turns purple in the presence of a bioweapon. This device has actually been used in Iraq. That's why the Iraqis kicked out the UN teams -- they were starting to use biosensor technology, and getting close to finding the fingerprints of real bioweapons in Iraq.



Dr. Duncan from Minneapolis: Mr. Preston -- your work is intriguing! Has there been any previous research/studies conducted on the subject? Did you have any material to draw from? Can you recommend further reading?

Richard Preston: Dr. Duncan, much of the best research in bioweaponry was done by the U.S. military in the 1960s, and the work is still classified. The Russians have recently published some interesting papers on freeze-dried Ebola and Marburg air tests. Scary. You can find that work in Medline, I believe.



Nance from E.H.: Are you worried at all about what is going on in Iraq -- do you think it has the potential to explode into something biologically dangerous? Or is it strictly chemical weaponry they have?

Richard Preston: Nance, the Iraqis are doing advanced research probably involving genetic engineering of viruses. This is a public-health threat to the entire world, because bioweapons can spread through a lethal chain of infection. That's why the UN should keep international pressure on Iraq to cool it.



Roger John from Red Rock: Hi, Richard, I share your somewhat morbid fascination with viruses and the idea of biowarfare -- why do you think that is? As a writer what draws you to it?

Richard Preston: Not all my works are morbid. FIRST LIGHT is about galaxies and stars. But I'm drawn to the invisible universe, the microscopic world within, and I'm drawn to the idea of the invisible monsters and predators that inhabit the world of viruses. This is great material for a writer.



Gregory from 10th Ave: Good evening, please tell us how one might contract the Lesch-Nyhan Syndrome aside from a bioattack?

Richard Preston: Gregory, natural Lesch-Nyhan is strictly a genetic disease. You have to be born with it. It's caused by damage to a single gene, one called the HPRT gene. It causes the child to gnaw on his extremities and chew off his own face. No one can explain the origin of this bizarre behavior.



Dana from Wilmington: I'm sure most people don't know the National Security Directive 7 -- will you elaborate and tell us who wrote this operation?

Richard Preston: NSD 7 originated in the White House. It's a Presidential Directive, so it comes directly from Bill Clinton. Parts of NSD-7 are classified. That is, the government keeps secret some aspects of a response to bioterror.



Nials Windgren from Chestnut Hill: Congrats on the windfall from the COBRA rights! How has it changed your life, if at all?

Richard Preston: Hollywood paid me $3 million for COBRA EVENT. It has not changed my life yet because we haven't received the check! I hope the heck it doesn't change my life. We're getting a lot of calls from charities!



Frances O'Patrick from Chicago: My imagination is still haunted by the images in THE HOT ZONE -- do you ever scare yourself or become paranoid?

Richard Preston: Naw, I've gotten used to it. It seems normal to me now.



Ray from State College, PA: What are you working on now? Fiction or non, articles or otherwise? What is you feeling about the sale of THE COBRA EVENT? Will you participate in its production into film?

Richard Preston: I'm trolling for new book ideas. Do you have any? Selling the rights to COBRA EVENT to Hollywood was kind of exciting. However, I am something of a nerd. My hollywood agent called me, very excited, and said that Tom Cruise was dying to play the FBI agent in COBRA EVENT, and Nicole Kidman would be Dr. Alice Austen. I said, "Who's Nicole Kidman." My agent was appalled. "How can anyone NOT KNOW who Nicole Kidman is?" he said. I guess I'd been talking to too many bioweapons scientists or something. I will participate in the production only to the extent that I'll give advice which they probably won't heed. I may do a cameo walk-through, which Stephen King does in his movies. I'd like to play a reporter scribbling notes in a corner while the bioterror operation is going down.



Harb from the Villiage: Hey Richard, thanks for taking my question. I think your work is exciting and a lot of fun, but how real is the threat of biological warfare?

Richard Preston: It's unfortunately terribly real. Bioweapons are real, and genetic engineering has entered the normal process of weapons development in military labs worldwide. There are about 25 countries working on bioweapons. These are the weapons of the future, in my opinion. Bioweapons are probably more likely to be used in terrorism than in warfare, but no one really knows.



Meverettpayne from North Carolina: Were any of your family members scientists or medical doctors? Did youever want to pursue any of the above career fields at any time?

Richard Preston: No scientists in the family. My brother Douglas Preston is the bestselling author of THE RELIC (made into the Paramount movie). Doug and I talk about science all the time, and we've been fascinated with it since childhood. We like to talk shop with each other about writing. Also, our youngest brother David is a medical doctor, and he has helped us both with the medical science in our books. The Preston brothers stick together!



Anne Sanders from Princeton: did you have a goal or audience in mind when you wrote this book, or THE HOT ZONE?

Richard Preston: My goal is that of most writers, to simply tell an unforgettable story. It's through stories that we learn and remember things about the world, history, and human nature. Stories are ancient and primitive, and can be immensely powerful. My audience is simply the collection of people, whoever they are, who happen to be fascinated with the things that fascinate me.



Lawrence from school: What planted the seed for this novel?

Richard Preston: I learned about bioweapons while I was writing THE HOT ZONE. I became determined to pursue the subject of bioweapons and learn more. I soon decided that I wanted to try fiction, but I wanted it to be based on a bedrock of convincing fact.



Moderator: Thanks for indulging our curiosities tonight! Best wishes for continued success and very happy holidays!

Richard Preston: Happy Holidays to everyone. May the truth prevail. And may that next cold be just a cold.... 'Bye.


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