This book is devoted to the structural, molecular, physiological and evolutionary aspects of spirochetes. Written by leading scientists in the field, it summarizes important aspects of spirochetes as a phylogenetic group of organisms and also surveys key representative pathogenic spirochetes in greater detail. The spirochetes include the causative agents of various important diseases, i.e. syphilis, periodontitis, Lyme disease, Leptospirosis and swine dysentery. This volume highlights in particular the recent advances in genetics, molecular biology and genomics in spirochete research.