Insect transgenesis promises improvements in agriculture, pharmaceuticals and public health. Many important insects can now be routinely transformed with effectors that have useful applications. Agriculture presents the largest market for transgenic insects and has a foundational history of success with sterile insect technique for control of pests including Mediterranean fruit flies and screwworms. Biotechnology will contribute superior markers, suppressible sterility and sex-conversion. Public health is also seeing transgenic mosquitoes developed which suppress natural populations and are incapable of transmitting disease. Experts in the field will contribute their insights into the latest technology and its applications. Authors will also consider the larger risks, social and economic aspects of transgenic insects whose value must be proven in political, regulatory and public acceptance arenas.
About the Author
Mark Q. Benedict
Table of Contents
Germline Transformation Technology 1) Transposons for Insect Transformation2) Transposon-based Technologies for Insects3) Sex-, Tissue- and Stage-Specific Transgene Expression4) Docking Systems for Site-Directed Transgene Integration5) Inducible and Repressible Systems for Transgene ExpressionApplications of Transgenic Insects 6) Sex Ratio Manipulation for Insect Population Control7) Conditional Dominant Lethals – RIDL8) Tephritid Fruit Fly Transgenesis and Applications9) Silkworm Transgenesis and Applications 10) Transgenic Approaches for Sterile Insect Control of Dipteran Livestock Pests and Lepidopteran Crop Pests11) Anti-Pathogen Effector Molecules: Current and Future Strategies12) Sexual Sterilization of MosquitoesAlternative Transgenic Approaches to Modifying Insect Phenotypes 13) Paratransgenesis in Mosquitoes and Other Insects: Microbial Ecology and Bacterial Genetic Considerations14) Asaia Paratrangenesis in Mosquitoes15) Paratransgenic Control of Chagas Disease16) Tsetse Paratransgenesis: A Novel Strategy for Reducing the Spread of African TrypanosomiasesConsiderations for the Release of Transgenic Insects 17) RIDL: Modelling Release of Insects Carrying a Dominant Lethal18) Assessing Risk of Transgenic Insects19) Economics of Transgenic Insects for Field Release20) Risk Analysis and the Regulation of Transgenic Insects21) Public Acceptability of New Insect Vector Control Technologies22) The Cartagena Protocol on the Transboundary Movement of Living Modified OrganismsRegulation of Trade in Transgenic Organisms Under International and European Environmental Law