Tutorial on electrophysiology (2014 edition)
A note on the 2014 edition.
While the Q & A format of this monograph remains the same, a number of significant changes have been made, as listed below:
1. A section on patch clamp has now been added, including the basic concepts of patch clamp and a comparison between this technique and sharp electrode recording.
2. The relationship between single channel recording and macroscopic current has now been explained explicitly, along with two additional figures.
3. Three movies detailing the progression of an action potential, together with corresponding changes in the underlying Na+ and K+ conductance and currents, have been incorporated.
4. At the end of Chapter 3: Action Potential with Na+ and K+ currents, graphic representations of Na+ and K+ channel states, together with the corresponding single channel current, have been added to the summary remarks for the description of an action potential.

This monograph is a tutorial for students who find electrophysiology difficult. In order to provide an alternative approach to the typical narrative of textbooks, materials in this document are organized in a Q&A format. More importantly, I try to explain electrophysiology with extensive use of graphs. I believe that many biology and health sciences majors fear electrophysiology because they are not used to manipulating concepts crystallized in equations, even though they are good at organizing causal relationships and molecular information. Over the years, I have noticed that the graphs I draw to help my students during office hours are very different from the ones that appear in textbooks. This difference arises because textbooks select graphs that are economical for the flow of text and make efficient use of space, whereas the graphs on the white board in my office are initiated by students or else constructed directly in response to their questions. The goal of this little book is to use a �graph heavy� approach to accurately represent subtle electrophysiology concepts without resorting to equations. It should be used as a supplementary resource in association with conventional textbooks assigned to undergraduates, graduate students and medical students.

Notes on the use of this tutorial:
1. Some graphs may look busy, but I assure you that all the labels have a purpose in helping you to understand important concepts. Despite the emphasis on graphs, the text is still important. The best way to use this study aid is to read the description of a figure carefully and patiently while examining the graphics.
2. Given the elaborate figures, this book is perhaps best used on your laptop or desktop. Small devices such as an iPhone or Nook are not ideal, because you will have difficulty displaying figures at the same time as text. Calibre. Adobe Digital Edition, NOOK for PC and Firefox Epubreader plugin all work and play videos.
3. This tutorial is quite long. Some questions may seem too "advanced" for many purposes. I have included them because I have had those "one question leads to another" occasions where, to my great joy, a student finds him or herself reaching for a level of understanding they had not expected for themselves at the beginning of the office hour session. I hope that at least some users of this tutorial will find themselves similarly inspired.
1105484387
Tutorial on electrophysiology (2014 edition)
A note on the 2014 edition.
While the Q & A format of this monograph remains the same, a number of significant changes have been made, as listed below:
1. A section on patch clamp has now been added, including the basic concepts of patch clamp and a comparison between this technique and sharp electrode recording.
2. The relationship between single channel recording and macroscopic current has now been explained explicitly, along with two additional figures.
3. Three movies detailing the progression of an action potential, together with corresponding changes in the underlying Na+ and K+ conductance and currents, have been incorporated.
4. At the end of Chapter 3: Action Potential with Na+ and K+ currents, graphic representations of Na+ and K+ channel states, together with the corresponding single channel current, have been added to the summary remarks for the description of an action potential.

This monograph is a tutorial for students who find electrophysiology difficult. In order to provide an alternative approach to the typical narrative of textbooks, materials in this document are organized in a Q&A format. More importantly, I try to explain electrophysiology with extensive use of graphs. I believe that many biology and health sciences majors fear electrophysiology because they are not used to manipulating concepts crystallized in equations, even though they are good at organizing causal relationships and molecular information. Over the years, I have noticed that the graphs I draw to help my students during office hours are very different from the ones that appear in textbooks. This difference arises because textbooks select graphs that are economical for the flow of text and make efficient use of space, whereas the graphs on the white board in my office are initiated by students or else constructed directly in response to their questions. The goal of this little book is to use a �graph heavy� approach to accurately represent subtle electrophysiology concepts without resorting to equations. It should be used as a supplementary resource in association with conventional textbooks assigned to undergraduates, graduate students and medical students.

Notes on the use of this tutorial:
1. Some graphs may look busy, but I assure you that all the labels have a purpose in helping you to understand important concepts. Despite the emphasis on graphs, the text is still important. The best way to use this study aid is to read the description of a figure carefully and patiently while examining the graphics.
2. Given the elaborate figures, this book is perhaps best used on your laptop or desktop. Small devices such as an iPhone or Nook are not ideal, because you will have difficulty displaying figures at the same time as text. Calibre. Adobe Digital Edition, NOOK for PC and Firefox Epubreader plugin all work and play videos.
3. This tutorial is quite long. Some questions may seem too "advanced" for many purposes. I have included them because I have had those "one question leads to another" occasions where, to my great joy, a student finds him or herself reaching for a level of understanding they had not expected for themselves at the beginning of the office hour session. I hope that at least some users of this tutorial will find themselves similarly inspired.
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Tutorial on electrophysiology (2014 edition)

Tutorial on electrophysiology (2014 edition)

by Jen-Wei Lin
Tutorial on electrophysiology (2014 edition)

Tutorial on electrophysiology (2014 edition)

by Jen-Wei Lin

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Overview

A note on the 2014 edition.
While the Q & A format of this monograph remains the same, a number of significant changes have been made, as listed below:
1. A section on patch clamp has now been added, including the basic concepts of patch clamp and a comparison between this technique and sharp electrode recording.
2. The relationship between single channel recording and macroscopic current has now been explained explicitly, along with two additional figures.
3. Three movies detailing the progression of an action potential, together with corresponding changes in the underlying Na+ and K+ conductance and currents, have been incorporated.
4. At the end of Chapter 3: Action Potential with Na+ and K+ currents, graphic representations of Na+ and K+ channel states, together with the corresponding single channel current, have been added to the summary remarks for the description of an action potential.

This monograph is a tutorial for students who find electrophysiology difficult. In order to provide an alternative approach to the typical narrative of textbooks, materials in this document are organized in a Q&A format. More importantly, I try to explain electrophysiology with extensive use of graphs. I believe that many biology and health sciences majors fear electrophysiology because they are not used to manipulating concepts crystallized in equations, even though they are good at organizing causal relationships and molecular information. Over the years, I have noticed that the graphs I draw to help my students during office hours are very different from the ones that appear in textbooks. This difference arises because textbooks select graphs that are economical for the flow of text and make efficient use of space, whereas the graphs on the white board in my office are initiated by students or else constructed directly in response to their questions. The goal of this little book is to use a �graph heavy� approach to accurately represent subtle electrophysiology concepts without resorting to equations. It should be used as a supplementary resource in association with conventional textbooks assigned to undergraduates, graduate students and medical students.

Notes on the use of this tutorial:
1. Some graphs may look busy, but I assure you that all the labels have a purpose in helping you to understand important concepts. Despite the emphasis on graphs, the text is still important. The best way to use this study aid is to read the description of a figure carefully and patiently while examining the graphics.
2. Given the elaborate figures, this book is perhaps best used on your laptop or desktop. Small devices such as an iPhone or Nook are not ideal, because you will have difficulty displaying figures at the same time as text. Calibre. Adobe Digital Edition, NOOK for PC and Firefox Epubreader plugin all work and play videos.
3. This tutorial is quite long. Some questions may seem too "advanced" for many purposes. I have included them because I have had those "one question leads to another" occasions where, to my great joy, a student finds him or herself reaching for a level of understanding they had not expected for themselves at the beginning of the office hour session. I hope that at least some users of this tutorial will find themselves similarly inspired.

Product Details

BN ID: 2940150721906
Publisher: Boston and Wales
Publication date: 10/23/2014
Sold by: Barnes & Noble
Format: eBook
File size: 2 MB

About the Author

Dr. Jen-Wei Lin received his undergraduate degree in Zoology from National Taiwan University and his Doctoral degree in Physiology from SUNY Buffalo. Before taking up a faculty position at Boston University�s Biology Department, he did postdoctoral research at New York University Medical School. Dr. Lin's research focus is the study of synaptic transmission and axonal membrane excitability using electrophysiological and imaging techniques.
Since 1993, Dr. Lin has taught undergraduate and graduate neuroscience and electrophysiology courses at Boston University, in both lecture and laboratory format. In addition, he has taught summer courses at the Marine Biology Laboratories in Woods Hole, Massachusetts. This monograph emerged as a result of the many interactions he has had with students during his extensive teaching experience.
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