Ultrafast and Memory-Efficient Alignment of Short DNA Sequences to the Human Genome

Ultrafast and Memory-Efficient Alignment of Short DNA Sequences to the Human Genome

by Applied Research Press

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Overview

Ultrafast and Memory-Efficient Alignment of Short DNA Sequences to the Human Genome by Applied Research Press

Bowtie is an ultrafast, memory-efficient alignment program for aligning short DNA sequence reads to large genomes. For the human genome, Burrows-Wheeler indexing allows Bowtie to align more than 25 million reads per CPU hour with a memory footprint of approximately 1.3 gigabytes. Bowtie extends previous Burrows-Wheeler techniques with a novel quality-aware backtracking algorithm that permits mismatches. Multiple processor cores can be used simultaneously to achieve even greater alignment speeds. Bowtie is open source http://bowtie.cbcb.umd.edu. Proceeds from the sale of this book go to support an elderly disabled person.

Product Details

ISBN-13: 9781515199977
Publisher: CreateSpace Publishing
Publication date: 07/23/2015
Pages: 40
Product dimensions: 8.50(w) x 11.00(h) x 0.10(d)

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