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Elsevier Science & Technology Books
Understanding DNA: The Molecule and How It Works / Edition 2

Understanding DNA: The Molecule and How It Works / Edition 2

by Christopher R. Calladine, Horace R. Drew


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Understanding DNA: The Molecule and How It Works / Edition 2

The functional properties of any molecule are directly related to, and affected by, its structure. This is especially true for DNA, the molecule that carries the code for all life on earth.
The Second Edition of Understanding DNA has been entirely revised and updated, and expanded to cover new advances in our understanding. It explains, step by step, how DNA forms specific structures, the nature of these structures and how they fundamentally affect the biological processes of transcription and replication.
Understanding DNA
* Describes the basic units of DNA and how these form the double helix
* Characteries the various types of DNA double helix that have been found
* Explains how and why DNA twists and curves
* Discusses the mechanisms of DNA supercoiling
* Summarizes the assembly of DNA and protein into chromosomes
* Describes the latest work on protein-DNA complexes
* Outlines the methods used to study DNA structure
* Summarizes recent studies of DNA in disease and medicine
* Contains over 120 illustrations, some in full color
* Contains simple exercises and further reading at the end of chapters
Written in a clear, concise and lively fashion, Understanding DNA is essential reading for all molecular biology, biochemistry and genetics students, to newcomers to the field from other areas such as chemistry, or physics, and even for the most seasoned researchers, who really want to understand DNA.

Product Details

ISBN-13: 9780121550882
Publisher: Elsevier Science & Technology Books
Publication date: 04/01/1997
Edition description: Older Edition
Pages: 283
Product dimensions: 6.59(w) x 9.56(h) x 0.56(d)

Table of Contents

An Introduction to Molecular Biology for Non-Scientists.
Why a Helix?
Different Kinds of Double Helix.
Twisting and Curving.
Curving in Three Dimensions.
DNA Supercoiling.
The Assembly of DNA into Chromosomes.
Specific DNA-Protein Interactions.
Methods Used to Study the Structure of DNA.
DNA in Disease, Diagnostics, and Medicine.
Notes on the Derivation of Some Technical Terms.
The Chemical Theory of Base-Stacking Interactions in DNA.
Answers to Selected Exercises.
Subject Index.

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