Worcester v. Georgia, 31 U.S. (6 Pet.) 515 (1832), was a case in which the United States Supreme Court held that Cherokee Native Americans were entitled to federal protection from the actions of state governments which would infringe on the tribe's sovereignty.
In 1835, a dissident faction of Cherokees signed a removal treaty, the Treaty of New Echota. Jackson actively lobbied the U.S. Senate to ratify the treaty in 1836, where it passed by a majority of one vote. In 1838, under President Martin Van Buren, this led to the forcible relocation by the U.S. Army of the Cherokees to Indian Territory (part of present-day Oklahoma) in what would become known as the Trail of Tears.