Pub. Date:
Basic Books
Vascular Endothelium: Receptors and Transduction Mechanisms

Vascular Endothelium: Receptors and Transduction Mechanisms

by J. D. Catravas


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Product Details

ISBN-13: 9780306432538
Publisher: Basic Books
Publication date: 01/01/1989
Series: NATO Science Series: A: Life Sciences
Pages: 320

Table of Contents

I. Properties of Endothelial Cell Plasmalemma.- Structural Basis for Endothelial Cell Function: Role of Calcium, Polyphosphoinositide Turnover and G-Proteins.- Modulation of Endothelial Permeability: Role of Receptors, Second Messengers and Ion Channels.- Factors Affecting the Fluidity of the Endothelial Cell Plasma Membrane.- Vascular Endothelial Surface Proteins in the Perfused Rabbit Lung.- Endothelial Specific Binding Sites for Permeant Plasma Macromolecules: Albumin Binding Proteins.- II. Receptors.- Purine Receptors on Endothelial Cells.- Muscarinic Receptors on Endothelial Cells.- Comparison between PAF-Acether Receptors on Intact Washed Human Platelets and Human Endothelial Cells in Culture.- Prostaglandins as Transducers of Proliferation Signals in Microvascular Endothelial Cells and the Pharmacological Control of Angiogenesis.- The Role of Basement Membrane in Angiogenesis.- The Role of Cytokines in the Symbiotic Relationship between Leukocytes and Vascular Endothelia.- Response of Vascular Cells to Herpes Simplex Virus Infection.- Receptors for Extracellular Matrix Proteins in Endothelial Cells.- Cellular Distribution and Heterogeneity of Endothelial Cell Adhesion Receptors.- III. Messengers.- Modulation of the Guanylate Cyclase -cGMP System by Vasodilators and the Role of Free Radicals as Second Messengers.- Agonist Stimulated Changes in Human Endothelial Cell Cytosolic Calcium.- Multiple Messenger Roles for the Inhibitory GTP-Binding Protein, Gi, in Human Platelets.- Diacylglycerols and Protein Kinase-C.- Transduction of Purinoceptor-Mediated Endothelial Cell Responses.- Protein Phosphorylation in Endothelial Cell Membranes: Relationship to Growth Control.- Endothelium-Dependent Vasodilation and the Nature of the Endothelium-Derived Relaxing Factor.- Endothelium-Derived Vasodilators.- Generation and Transmission of Endothelium-Dependent Vasodilator Signals.- IV. Abstracts of Oral and Poster Presentations.- V. Listofparticipants.- VI. Index.

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