Yeast: Molecular and Cell Biology

Yeast: Molecular and Cell Biology

by Horst Feldmann

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Overview

Yeast is one of the oldest domesticated organisms and has both industrial and domestic applications. In addition, it is very widely used as a eukaryotic model organism in biological research and has offered valuable knowledge of genetics and basic cellular processes. In fact, studies in yeast have offered insight in mechanisms underlying ageing and diseases such as Alzheimers, Parkinsons and cancer. Yeast is also widely used in the lab as a tool for many technologies such as two-hybrid analysis, high throughput protein purification and localization and gene expression profiling.
The broad range of uses and applications of this organism undoubtedly shows that it is invalubale in research, technology and industry. Written by one of the world's experts in yeast, this book offers insight in yeast biology and its use in studying cellular mechanisms.

Product Details

ISBN-13: 9783527644865
Publisher: Wiley
Publication date: 09/19/2011
Sold by: Barnes & Noble
Format: NOOK Book
Pages: 348
File size: 2 MB

About the Author

Horst Feldmann studied Organic Chemistry in Cologne and did his PhD in this discipline. From 1962 to 1967 he worked at the Institute of Genetics in Cologne. In 1974 he became Professor of Physiological Chemistry at the Medical Faculty in Munich. His pioneering research included sequencing yeast tRNA. He extensively studied tRNA and protein biogenesis, yeast retrotransposons and mitochondrial genome and was a co-ordinator in the EU project "Sequencing and Analysis of the Yeast Genome". From 1971 until 2007 he was one of the organizers of the International "Spetses Summer Schools on Molecular and Cell Biology". Horst Feldmann was a member of the Board of FEBS and served as chairman of the Advanced Courses Committee, Secretary of the Prize "Biochemical Analysis" and the Head of SFB "Mechanisms and Factors in Gene Regulation". He has also served as member of a number of different committees, namely the DFG, IUBMB, DISNAT (German-Israeli cooperation). He is also an Honorary Member of Hellenic Society for Biochemistry and Biophysics. In 1996 he received the FEBS Diplôme d'Honneur.

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Table of Contents

Introduction
The "Early Days" of Nucleic Acids
Genetic Engineering and Reverse Genetics
Cell Structures and Functions
Cellular Dynamics
Anatomy of the Transcription Machinery and Auxiliary Complexes -
Chromatin Remodeling
Molecular Signalling Cascades and Gene Regulation
Yeast Organellar Function and Biogenesis
The Yeast Genome and Post-Genomics
Disease Genes in Yeast
Yeast Biotechnology
Epilogue: The Future of Yeast Research

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