Bioinformatics for Geneticists / Edition 1

Bioinformatics for Geneticists / Edition 1

by Michael R. Barnes
     
 

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ISBN-10: 0470843934

ISBN-13: 9780470843932

Pub. Date: 04/04/2003

Publisher: Wiley

This work describes a step-by-step approach to key bioinformatics and genetic analysis procedures, and features detailed case studies of problems and analytical approaches specific to the needs of the genetics researcher. Bioinformatics tools and genetic databases are also reviewed. Material is written to capture the principles of analysis regardless of the tool used,

Overview

This work describes a step-by-step approach to key bioinformatics and genetic analysis procedures, and features detailed case studies of problems and analytical approaches specific to the needs of the genetics researcher. Bioinformatics tools and genetic databases are also reviewed. Material is written to capture the principles of analysis regardless of the tool used, ensuring that the book stays relevant. The editors are affiliated with GlaxoSmithKline Pharmaceuticals, UK. Annotation (c)2003 Book News, Inc., Portland, OR

Product Details

ISBN-13:
9780470843932
Publisher:
Wiley
Publication date:
04/04/2003
Series:
Hierarchical Exotoxicology Mini Series, #1
Pages:
422
Product dimensions:
6.22(w) x 9.09(h) x 1.13(d)

Table of Contents

SECTION I: AN INTRODUCTION TO BIOINFORMATICS FOR THE GENETICIST
Introduction: The Role of Genetic Bioinformatics (Michael R. Barnes and Ian C. Gray)
Internet Resources for the Geneticist (Michael R. Barnes and Christopher Southan)
Human Genetic Variation – Databases and Concepts (Michael R. Barnes)
Finding, Delineating and Analysing Genes (Christopher Southan)
SECTION II: THE IMPACT OF COMPLETE GENOME SEQUENCES ON GENETICS
Assembling a View of the Human Genome (Colin A. Semple)
Mouse and Rat Genome Informatics (Judith A. Blake, Janan Eppig and Carol J. Bult)
Genetic and Physical Map Resources - An Integrated View (Michael R. Barnes)
SECTION III: BIOINFORMATICS FOR GENETIC STUDY DESIGN
From Linkage Peak to Culprit Gene: Following Up Linkage Analysis of Complex Phenotypes with Population-based Association Studies (Ian C. Gray)
Genetic Studies from Genomic Sequence (Michael R. Barnes)
SNP Discovery and PCR-based Assay Design: From In Silico Data to the Laboratory Experiment (Ellen Vieux, Gabor Marth and Pui Kwok)
Tools for Statistical Analysis of Genetic Data (Aruna Bansal, Peter R. Boyd and Ralph McGinnis)
SECTION IV: BIOLOGICAL SEQUENCE ANALYSIS AND CHARACTERIZATION
Predictive Functional Analysis of Polymorphisms - An Overview (Michael R. Barnes)
Functional In Silico Analysis of Non-Coding SNPs (Thomas Werner)
Amino Acid Properties and Consequences of Substitutions (Matthew J. Betts and Robert B. Russell)
SECTION V: GENETICS/GENOMICS INTERFACES
Gene Expression Informatics and Analysis (A. H. C. van Kampen, J. M. Ruijter, B. D. C. van Schaik, H. N. Caron and R. Versteeg)
Proteomic Informatics (Jerome Wojcik and AlexandreHamburger)
Concluding Remarks: Final Thoughts and Future Trends (Michael R. Barnes and Ian C. Gray).

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