Triumph of the Heart: The Story of Statins

Triumph of the Heart: The Story of Statins

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by Jie Jack Li
     
 

Over 25 million people in the U.S. alone have benefited from statins—such drugs as Lipitor, Zocor, Crestor, Pravachol, and other cholesterol-lowering medicines—in preventing stroke, heart attack, and other forms of coronary heart disease. But how did these remarkable, life-saving drugs come into being? In Triumph of the Heart, Dr. Jie Jack Li, a medicinal

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Overview

Over 25 million people in the U.S. alone have benefited from statins—such drugs as Lipitor, Zocor, Crestor, Pravachol, and other cholesterol-lowering medicines—in preventing stroke, heart attack, and other forms of coronary heart disease. But how did these remarkable, life-saving drugs come into being? In Triumph of the Heart, Dr. Jie Jack Li, a medicinal chemist and expert on drug discovery, tells for the first time the fascinating story of statins. Drawn from discussions with many scientists involved in the discovery and development of these drugs, the book illuminates the human side of science by revealing the role played by persistence, luck, and sudden insight that characterize major discoveries. For scientists in the drug industry, health care professionals, students of medicine, and all those intrigued by the basic human drive to explore and discover, Triumph of the Heart offers a compelling view of one of the most important drug discoveries of our time.

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Product Details

ISBN-13:
9780195323573
Publisher:
Oxford University Press, USA
Publication date:
04/03/2009
Pages:
224
Product dimensions:
6.10(w) x 9.30(h) x 1.00(d)

Table of Contents

Prologue
1. Cholesterol
2. Genesis of Statins
3. Merck's Triumph
4. Discovery of Lipitor
5. Development of Lipitor
6. To Market, To Market
7. Baycol, Crestor, and Drugs beyond Statins
8. Reflections
Appendix
Trademarks of the Drugs
Bibliography and Notes
Index

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