This volume, the second in the Springer series Philosophy of Science in a European Perspective, contains selected papers from the workshops organised by the ESF Research Networking Programme PSE (The Philosophy of Science in a European Perspective) in 2009. Five general topics are addressed: 1. Formal Methods in the Philosophy of Science; 2. Philosophy of the Natural and Life Sciences; 3. Philosophy of the Cultural and Social Sciences; 4. Philosophy of the Physical Sciences; 5. History of the Philosophy of Science. This volume is accordingly divided in five sections, each section containing papers coming from the meetings focussing on one of these five themes. However, these sections are not completely independent and detached from each other. For example, an important connecting thread running through a substantial number of papers in this volume is the concept of probability: probability plays a central role in present-day discussions in formal epistemology, in the philosophy of thephysical sciences, and in general methodological debates—-it is central in discussions concerning explanation, prediction and confirmation. The volume thus also attempts to represent the intellectual exchange between the various fields in the philosophy of science that was central in the ESF workshops.