Newspapers fought one another for scoops, people across the country claimed to have seen the missing woman alive, and each new clue led to fresh rounds of speculation about the crime. Meanwhile, sausage sales plummeted nationwide as rumors circulated that Luetgert had destroyed his wife's body in one of his factory's meat grinders.

Weaving in strange-but-true subplots involving hypnotists, palmreaders, English con artists, bullied witnesses, and insane-asylum bodysnatchers, Alchemy of Bones is more than just a true crime narrative; it is a grand, sprawling portrait of 1890s Chicago—and a nation—getting an early taste of the dark, chaotic twentieth century.