Table of Contents
Contributors ix
PREFACE xiii
Acknowledgments xix
1 Historical Perspective on Nanoparticles in Imaging from 1895 to 2000 1Mikhail Y. Berezin
Part I Nanoparticle design, synthesis and characterization 25
2 Iron Oxide-Based Magnetic Nanoparticles Synthesized from the Organic Solution Phase for Advanced Biological Imaging 27Sen Zhang and Shouheng Sun
3 Lipid-Based Pharmaceutical Nanocarriers for Imaging Applications 49Tamer Elbayoumi and Vladimir Torchilin
4 Hollow Nanocapsules in Biomedical Imaging Applications 83Sergey A. Dergunov and Eugene Pinkhassik
5 Nanoparticles as Contrast Agents for Optoacoustic Imaging 111Anton V. Liopo and Alexander A. Oraevsky
6 Nanoparticles for Bioimaging: Analytical Characterization and Measurements 151Kate Nelson, Patrick Winter, Monica Shokeen, Steven Wang, and Mikhail Y. Berezin
Part II Imaging modalities: from concepts to applications 193
7 Radio-Labeled Nanoparticles for Biomedical Imaging 195Tolulope Aweda, Deborah Sultan, and Yongjian Liu
8 MRI with Gadolinium-Based Nanoparticles 223François Guérard, Geoffrey L. Ray, and Martin W. Brechbiel
9 In Vivo Molecular Fluorescence Imaging 263Yasaman Ardeshirpour, Victor Chernomordik, Moinuddin Hassan, Dan Sackett, and Amir H. Gandjbakhche
10 Photoacoustic and Ultrasound Imaging with Nanosized Contrast Agents 293Mansik Jeon and Chulhong Kim
11 Surface-Enhanced Raman Scattering-Based Bioimaging 325Limei Tian and Srikanth Singamaneni
Part III Nanotechnology in biomedical imaging and beyond 347
12 Pandia®: Gold Nanorods and their Applications in Cancer Therapy and In Vivo Imaging in Companion Animals and their Potential Application to Humans 349Christian Schoen and Cheryl London
13 Imaging Genetic Information 373John-Stephen Taylor
14 The Application of Plant Viral Nanoparticles in Tissue-Specific Imaging 401Amy M. Wen, Choi-Fong Cho, John D. Lewis, and Nicole F. Steinmetz
15 Design and Development of Theranostic Nanomedicines 429Jelena M. Janjic and Mingfeng Bai
16 Animal Models for Preclinical Imaging 467Grayson Talcott and Walter J. Akers
Index 487