A Guide to Blood and Marrow Transplantation

by H. Joachim Deeg, Hans-Georg Klingemann, Gordon L. Phillips, Gary Van Zant

Overview

The first edition to A Guide to Bone Marrow Transplantation was published 10 years ago. At that time we perceived a need for an introductory text to the area of marrow transplantation, a rapidly developing field with few general texts avail­ able. Since then the situation has changed dramatically. Several introductory texts, therapeutic manuals and comprehensive volumes have been published. There is a heightened awareness of the availability, utility and potential of bone marrow transplantation, and of peripheral blood stem cell transplantation in particular. In many cases stem cell transplantation is being practiced by physi­ cians as a standard therapy. For those reasons we weighed carefully the question whether the Guide was still useful or even had a place. The feedback we received from physicians in practice or in training (including both hematologists and other physicians), as well as from nurses, physician's assistants, nurse practitioners, and other personnel in­ volved in one way or another in hematopoietic stem cell transplantation indicat­ ed that such a text was still desirable as an introduction that focused on princi­ ples rather than the latest up-to-date results.

Product Details

ISBN-13:	9783642621222
Publisher:	Springer Berlin Heidelberg
Publication date:	09/07/2012
Edition description:	Third Edition 1999
Pages:	231
Product dimensions:	6.10(w) x 9.25(h) x 0.02(d)

Table of Contents

I. Pretransplant Considerations.- 1. Rationale and Indications for Transplantation.- 2. Timing of Transplantation.- 3. Stem Cell Sources.- 4. Preparation for Stem Cell Transplantation.- 5. Cost Considerations.- II. Transplant Procedure.- 1. Conditioning Regimens.- 2. Collection and Processing of Stem Cells.- 3. In Vitro Expansion of Stem Cells.- 4. Genetic Manipulation of Hematopoietic Stem Cells.- 5. Prevention and Treatment of Relapse.- III. Transplant-Related Problems.- 1. Side Effects of Conditioning Regimens.- 2. Graft Failure.- 3. Graft-Versus-Host Disease.- 4. Management of Infections.- 5. Single and Multi-Organ Failure.- 6. Chronic Graft-Versus-Host Disease.- 7. Delayed Complications.- IV. Long-Term Follow-Up.- 1. Follow-Up After Discharge from the Transplant Center.- 2. Rehabilitation.- QuoVadis?.- 225.