A Prescription for Change: The Looming Crisis in Drug Development

A Prescription for Change: The Looming Crisis in Drug Development

by Michael Kinch
A Prescription for Change: The Looming Crisis in Drug Development

A Prescription for Change: The Looming Crisis in Drug Development

by Michael Kinch


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The introduction of new medicines has dramatically improved the quantity and quality of individual and public health while contributing trillions of dollars to the global economy. In spite of these past successes—and indeed because of them—our ability to deliver new medicines may be quickly coming to an end. Moving from the beginning of the twentieth century to the present, A Prescription for Change reveals how changing business strategies combined with scientific hubris have altered the way new medicines are discovered, with dire implications for both health and the economy.

To explain how we have arrived at this pivotal moment, Michael Kinch recounts the history of pharmaceutical and biotechnological advances in the twentieth century. Kinch relates stories of the individuals and organizations that built the modern infrastructure that supports the development of innovative new medicines. He shows that an accelerating cycle of acquisition and downsizing is cannibalizing that infrastructure Kinch demonstrates the dismantling of the pharmaceutical and biotechnological research and development enterprises could also provide opportunities to innovate new models that sustain and expand the introduction of newer and better breakthrough medicines in the years to come.

Product Details

ISBN-13: 9781469647579
Publisher: The University of North Carolina Press
Publication date: 03/01/2018
Series: The Luther H. Hodges Jr. and Luther H. Hodges Sr. Series on Business, Entrepreneurship, and Public Policy
Edition description: Reprint
Pages: 352
Product dimensions: 6.00(w) x 9.10(h) x 0.90(d)

About the Author

Michael Kinch is Associate Vice Chancellor and Director of the Center for Research Innovation in Biotechnology at Washington University in St. Louis.

What People are Saying About This

From the Publisher

This compelling and thoughtful book provides a unique perspective and critical analysis of the pharmaceutical industry and its mode of expansion.—Ronald Goldfarb, Sopherion Therapeutics

In this era of Valeant and congressional skepticism about the motivations of the leaders of the pharmaceutical industry and their investors, and as the fundamental processes of drug discovery and development become less effective and the costs of discovering new and useful scientific truths escalate, Michael Kinch asks, 'How did we reach this point?' A Prescription for Change lays out the fundamental facts and history of the industry to provide a brilliant, revealing, commonsense, and well-written answer to this timely and essential question.—Dr. Richard N. Foster, Chair, Presidents' Circle, National Academies of Science, Engineering, and Medicine

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