Advanced Biosensors for Health Care Applications

by Raju Khan PhD, FRSC, Ali Mohammad, Abdullah M. Asiri, Inamuddin

Overview

Advanced Biosensors for Health Care Applications highlights the different types of prognostic and diagnostic biomarkers associated with cancer, diabetes, Alzheimer's disease, brain and retinal diseases, cardiovascular diseases, bacterial infections, as well as various types of electrochemical biosensor techniques used for early detection of the potential biomarkers of these diseases. Many advanced nanomaterials have attracted intense interests with their unique optical and electrical properties, high stability, and good biocompatibility. Based on these properties, advanced nanoparticles have been used as biomolecular carriers, signal producers, and signal amplifiers in biosensor design. Recent studies reported that there are several diagnostic methods available, but the major issue is the sensitivity and selectivity of these approaches.

This book outlines the need of novel strategies for developing new systems to retrieve health information of patients in real time. It explores the potential of nano-multidisciplinary science in the design and development of smart sensing technology using micro-nanoelectrodes, novel sensing materials, integration with MEMS, miniaturized transduction systems, novel sensing strategy, that is, FET, CMOS, System-on-a-Chip (SoC), Diagnostic-on-a-Chip (DoC), and Lab-on-a-Chip (LOC), for diagnostics and personalized health-care monitoring. It is a useful handbook for specialists in biotechnology and biochemical engineering.

Product Details

ISBN-13:	9780128157435
Publisher:	Elsevier Science
Publication date:	06/18/2019
Pages:	432
Product dimensions:	7.50(w) x 9.25(h) x (d)

About the Author

Raju Khan is a Senior Principal Scientist and Professor, at CSIR-Advanced Materials and Processes Research Institute, Bhopal. He did his PhD in Chemistry in 2005 from Jamia Millia Islamia, Central University, New Delhi, and Postdoctoral researcher at the “Sensor Research Laboratory” University of the Western Cape, Cape Town. His current research involved synthesizing novel materials to fabricate electrochemical and fluorescence-based biosensors integrated with microfluidics to detect target disease risk biomarkers for health care monitoring. He has published over 150 papers in SCI journal, which attracted over 5500 citations as per Google Scholar, published 45 book chapters in the reputed book Elsevier and Taylor Francis, editing of 28 books from Elsevier and Taylor Francis, and his research has been highlighted in Nature India. He has supervised 5 PhD and 30 undergraduate/postgraduate theses and has supervised 4 numbers of postdoctoral fellows under the scheme of N-PDF, CSIR-Nehru Fellowship, and DST-Women Scientist Projects.

Ali Mohammad is Emeritus Professor of Chemistry in the Department of Applied Chemistry, Faculty of Engineering and Technology, Aligarh Muslim University, Aligarh, India. His scientific interests include physico-analytical aspects of solid-state reactions, micellar thin layer chromatography, surfactants analysis, and green chromatography. He is the author or coauthor of 250 scientific publications including research articles, reviews, and book chapters. He has also served as editor of Journal, Chemical and Environmental Research being published from India since 1992 and as the Associate Editor for Analytical Chemistry section of the Journal of Indian Chemical Society. He has been the member of editorial boards of Acta Chromatographica, Acta Universitatis Cibiniensis Seria F. Chemia, Air Pollution, and Annals of Agrarian Science. He has attended as well as chaired sessions in various international and nation conferences. Dr. Mohammad obtained his M.Phil. (1975), Ph.D. (1978), and D.Sc. (1996) degrees from Aligarh Muslim University, Aligarh, India. He has supervised 53 students for Ph.D./M.Phil. and M.Tech. degrees.

Prof. Abdullah M. Asiri is the Head of the Chemistry Department at King Abdulaziz University since October 2009 and he is the founder and the Director of the Center of Excellence for Advanced Materials Research (CEAMR) since 2010 till date. He is the Professor of Organic Photochemistry. His research interest covers color chemistry, synthesis of novel photochromic and thermochromic systems, synthesis of novel coloring matters and dyeing of textiles, materials chemistry, nanochemistry and nanotechnology, polymers and plastics. A major achievement of Prof. Asiri is the discovery of tribochromic compounds, a class of compounds which change from slightly or colorless to deep colored when subjected to small pressure or when grind. This discovery was introduced to the scientific community as a new terminology published by IUPAC in 2000. This discovery was awarded a patent from European Patent office and from UK patent. He is also a member of the Editorial Board of various journals of international repute. He is the Vice- President of Saudi Chemical Society (Western Province Branch). He holds four USA patents, more than 800 Publications in international journals, seven book chapters, and ten books

Dr. Inamuddin is an Assistant Professor at the Department of Applied Chemistry at the Zakir Husain College of Engineering and Technology, Aligarh Muslim University, Aligarh, India. He has extensive research experience in multidisciplinary fields of analytical chemistry, materials chemistry, electrochemistry, renewable energy, and environmental science. He has worked on different research projects funded by various government agencies and universities and is the recipient of several awards, including the Fast Track Young Scientist Award and the Young Researcher of the Year Award 2020, Aligarh Muslim University, India. He has published nearly 200 research articles in various international scientific journals, 18 book chapters, and numerous edited books with well-known publishers.

Table of Contents

1. Advanced nanoparticle-based biosensors for diagnosing foodborne pathogens2. Aptamer technology for the detection of foodborne pathogens and toxins3. Biosensors for rapid detection of breast cancer biomarkers4. Electrochemical biosensors for antioxidants5. Electrochemical immunosensors for rapid detection of breast cancer biomarkers6. Functionalized advanced hybrid materials for biosensing applications7. Smart, portable, and noninvasive diagnostic biosensors for healthcare8. Aptamer-mediated nanobiosensing for health monitoring9. Biosensing-drug delivery systems for in vivo applications10. Nanobodies and their in vivo applications11. New micro- and nanotechnologies for electrochemical biosensor development12. Cholesterol-based enzymatic and nonenzymatic sensors13. Recent trends in sensors for health and agricultural applications14. Hybrid carbon nanostructures for chemical and biological sensors15. Challenges and future prospects of nanoadvanced sensing technology

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From the Publisher

Presents new ideas to motivate development of the next generation of sensing materials for health care monitoring and diagnostic systems