Aging Lungs, The: Mechanisms And Clinical Sequelae

by Richard Bucala, Patty J Lee

Overview

This volume provides a comprehensive and multi-disciplinary overview of the aging lung, written by the main researchers in the field. Current physiological, cellular and molecular understanding of how the lungs age and the relationship to age-associated lung diseases will be presented. The contents are aimed at a broad audience of scientists and clinicians with an interest in the respiratory system, pathogenesis of age-associated lung diseases and clinical implications.

Product Details

ISBN-13:	9789814635004
Publisher:	World Scientific Publishing Company, Incorporated
Publication date:	02/19/2016
Pages:	524
Product dimensions:	6.10(w) x 9.10(h) x 1.10(d)

Table of Contents

Preface Patty J. Lee Richard Bucala v

Chapter 1 Normal Development, Anatomy, Histology and Aging of the Lung Xuchen Zhang Robert J. Homer 1

Chapter 2 Physiology of the Aging Lung Brienne Miner Thomas M. Gill Carlos A. Vaz Fragoso 39

Chapter 3 Aging Lung, Environmental and Genetic Factors - Race, Ethnicity and Gender Holly Keyt Stephanie Levine Claude Jourdan Le Saux 71

Chapter 4 Frailty in Pulmonary and Critical Care Medicine Cristine E. Berry Enid R. Neptune 91

Chapter 5 Intensive Care Unit Outcomes in Older Adults Margaret A. Pisani Lauren Ferrante 119

Chapter 6 Severe Sepsis, Pneumonia and Aging Olufunmilayo Falade Sachin Yende 139

Chapter 7 Sepsis and Acute Lung Injury in Aging Anup Srivastava Yao Wong Shruti Erramilli Praveen Mannam 159

Chapter 8 Acute Respiratory Distress Syndrome: The Role of Mesenchymal Stem Cells and Arising Complications Due to an Aging Lung John Sembrat Maria G. Kapetanaki Mauricio Rojas 181

Chapter 9 The Aging Immune System, Vaccine Efficacy, and the Lung Jenna M. Bartley Laura Haynes 197

Chapter 10 Respiratory Infection, Airway Colonization and Chronic Inflammation in Aging Chad Marion Charles S. Dela Cruz 223

Chapter 11 HIV, the Lung and Aging Lynn M. Schnapp Kristina Crothers 257

Chapter 12 Geriatric Pulmonary Hypertension: Recent Epidemiologic Trends and Treatment update Vanessa Yap George A. Kuchel Raymond J. Foley 283

Chapter 13 Growth Factors and Aging in Pulmonary Arterial Hypertension Claudio Bravo Won-Kyung Cho Hyung J. Chun 315

Chapter 14 Chronic Obstructive Lung Disease in the Elderly Jessica F. Most Carolyn L. Rochester 345

Chapter 15 Genomics of Lung Aging and Idiopathic Pulmonary Fibrosis Brenda Juan-Guardela Naftali Kaminski 389

Chapter 16 Potential Mechanistic Links Between Aging and IPF Hongyi Pan Mridu Gulati Erica L. Herzog 409

Chapter 17 Telomeres and Telomerase Mary Armanios 431

Chapter 18 Endoplasmic Reticulum Stress Maria Bueno Ana L. Mora 443

Chapter 19 Autophagy and Metabolism Jaime L. Schneider Cecilia G. Sanchez 473

Index 511