An Introduction to Testing for Drugs of Abuse

by William E. Schreiber

Overview

An Introduction to Testing for Drugs of Abuse

An Introduction to Testing for Drugs of Abuse presents a distilled set of facts about the major drugs of abuse that are encountered in clinical practice. Individual chapters highlight the similarities in chemical structure, mechanism of action, and physiologic effects of each drug group, as well as their metabolism, therapeutic uses and potential for misuse or abuse. Special attention is given to the testing process, with an emphasis on interpretation of test results.

Informative and entertaining cases appear at the end of each chapter. These cases illustrate the many situations in which drug testing is performed for medical, legal and employment purposes.

Written in clear, concise language, this book provides practical guidance to pathologists, clinical chemists and technologists who are responsible for reporting and interpreting the results of drug analyses. It will be especially useful to residents and students who are learning about toxicology for the first time. Clinical practitioners – doctors, nurses, pharmacists and other health care professionals – will find the information they need to order and interpret drug tests accurately.

For more information watch the trailer here:  https://players.brightcove.net/4931690914001/B1xdbomRDl_default/index.html?videoId=6310075842112

Product Details

ISBN-13:	9781119794059
Publisher:	Wiley
Publication date:	06/07/2022
Pages:	208
Product dimensions:	6.00(w) x 9.00(h) x 0.50(d)

About the Author

About the Author

William E. Schreiber is a Professor in the Department of Pathology and ­Laboratory Medicine at The University of British Columbia and Clinical Director of Chemistry at LifeLabs. Previously, he was a consultant pathologist at Vancouver General Hospital and medical director of the British Columbia Provincial Toxicology Centre. He is a past president of the American Society for Clinical Pathology.

Table of Contents

Preface vii

Section I Substance Use, Drug Metabolism, and the Testing Process 1

1 Introduction 3

2 How the Body Handles Drugs 13

3 Specimen Collection 19

4 Screening Tests: Immunoassays 27

5 Confirmation Tests: Chromatography and Mass Spectrometry 37

Section II Individual Drugs 47

6 Cocaine 49

7 Amphetamines 59

8 Benzodiazepines and Z-drugs 77

9 Other Sedative-Hypnotic Drugs 93

10 Opioids 105

11 Cannabinoids 125

12 Hallucinogens 137

13 Alcohols 151

Section III Appendices 177

Appendix A How to Read a Toxicology Report 179

Appendix B Guideline Documents: Pain Management and Addiction Medicine 183

Index 185