Animal Models of Drug Addiction
Our understanding of addiction and how it is treated has advanced remarkably over the past decades, and much of the progress is related directly to animal research. This is true for both the behavioural aspects of drug use as well as the biological underpinnings of the disorder. In Animal Models of Drug Addiction, experts in the field provide an up-to-date review of complex behavioural paradigms that model different stages of this disorder and explain how each test is used to effectively replicate the progression of drug addiction. This detailed and practical book begins with the most common laboratory measures of addiction in animals, including intracranial self-stimulation (ICSS), drug self-administration, place conditioning, and sensitization. Later chapters describe how these paradigms are used to model the progression of drug addiction, providing insight into the clinical symptomatology of addiction from acquisition of drug use through compulsive drug taking to withdrawal and relapse. Written for the popular Neuromethods series, the contributions offer both methodological detail and a theoretical perspective, appealing to readers familiar with preclinical research on drug addiction as well as those who are newcomers to the field. Cutting-edge and authoritative, Animal Models of Drug Addiction will serve as a basis for future vital research that links the bench to the bedside in the crucial treatment of drug addiction.
1101308003
Animal Models of Drug Addiction
Our understanding of addiction and how it is treated has advanced remarkably over the past decades, and much of the progress is related directly to animal research. This is true for both the behavioural aspects of drug use as well as the biological underpinnings of the disorder. In Animal Models of Drug Addiction, experts in the field provide an up-to-date review of complex behavioural paradigms that model different stages of this disorder and explain how each test is used to effectively replicate the progression of drug addiction. This detailed and practical book begins with the most common laboratory measures of addiction in animals, including intracranial self-stimulation (ICSS), drug self-administration, place conditioning, and sensitization. Later chapters describe how these paradigms are used to model the progression of drug addiction, providing insight into the clinical symptomatology of addiction from acquisition of drug use through compulsive drug taking to withdrawal and relapse. Written for the popular Neuromethods series, the contributions offer both methodological detail and a theoretical perspective, appealing to readers familiar with preclinical research on drug addiction as well as those who are newcomers to the field. Cutting-edge and authoritative, Animal Models of Drug Addiction will serve as a basis for future vital research that links the bench to the bedside in the crucial treatment of drug addiction.
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Animal Models of Drug Addiction

Animal Models of Drug Addiction

by Mary C. Olmstead (Editor)
Animal Models of Drug Addiction

Animal Models of Drug Addiction

by Mary C. Olmstead (Editor)

Hardcover(2011)

$109.99 
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Overview

Our understanding of addiction and how it is treated has advanced remarkably over the past decades, and much of the progress is related directly to animal research. This is true for both the behavioural aspects of drug use as well as the biological underpinnings of the disorder. In Animal Models of Drug Addiction, experts in the field provide an up-to-date review of complex behavioural paradigms that model different stages of this disorder and explain how each test is used to effectively replicate the progression of drug addiction. This detailed and practical book begins with the most common laboratory measures of addiction in animals, including intracranial self-stimulation (ICSS), drug self-administration, place conditioning, and sensitization. Later chapters describe how these paradigms are used to model the progression of drug addiction, providing insight into the clinical symptomatology of addiction from acquisition of drug use through compulsive drug taking to withdrawal and relapse. Written for the popular Neuromethods series, the contributions offer both methodological detail and a theoretical perspective, appealing to readers familiar with preclinical research on drug addiction as well as those who are newcomers to the field. Cutting-edge and authoritative, Animal Models of Drug Addiction will serve as a basis for future vital research that links the bench to the bedside in the crucial treatment of drug addiction.

Product Details

ISBN-13: 9781607619338
Publisher: Springer-Verlag New York, LLC
Publication date: 12/10/2010
Series: Neuromethods , #53
Edition description: 2011
Pages: 484
Product dimensions: 7.01(w) x 10.00(h) x 0.39(d)

Table of Contents

Preface vii

Contributors xi

Part I Behavioral Paradigms

1 Intracranial Self-Stimulation Styliani Vlachou Athina Markou 3

2 Stimulant Self-Administration Leigh V. Panlilio 57

3 Opiate Self-Administration Francesco Leri 83

4 Nicotine Self-Administration Robert E. Sorge Paul B. S. Clarke 101

5 Alcohol Self-Administration Friedbert Weiss 133

6 Place Conditioning Christopher L. Cunningham Peter A. Groblewski Charlene M. Voorhees 167

7 Sensitization Jessica A. Loweth Paul Vezina 191

8 Animal Models of Eating Disorders Stephanie D. Hancock Mary C. Olmstead 207

Part II Modeling Stages of Drug Addiction in Animals

9 Acquisition of Drug Self-Administration Marilyn E. Carroll Richard A. Meisch 237

10 Escalation of Drug Use Serge H. Ahmed 267

11 Environmental Modulation of Drug Taking Aldo Badiani Daniele Caprioli Arianna Testa Maria Teresa De Luca Michele Celentano 293

12 Craving Jeffrey W. Grimm 311

13 Habit Formation and Compulsion David Belin Daina Economidou Yann Pelloux Barry J. Everitt 337

14 Impulsivity Andrea Bari Trevor W. Robbins Jeffrey W. Dalley 379

15 Binge Drug Taking Herbert E. Covington III Klaus A. Miczek 403

16 Withdrawal Alasdair M. Barr Heidi N. Boyda Ric M. Procyshyn 431

17 Relapse Suzanne Erb Franca Placenza 461

Index 481

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