Table of Contents
Preface v
Acknowledgments vii
List of Physical Pharmacy Capsules ix
Section I Introduction to Drugs, Drug Dosage Forms, and Drug Delivery Systems 1
1 Introduction to Drugs and Pharmacy 2
2 New Drug Development and Approval Process 26
3 Current Good Manufacturing Practices and Current Good Compounding Practices 58
Section II Drug Dosage Form and Drug Delivery System Design 75
4 Dosage Form Design: Pharmaceutical and Formulation Considerations 76
5 Dosage Form Design: Biopharmaceutical and Pharmacokinetic Considerations 131
Section III Solid Dosage Forms and Solid Modified-Release Drug Delivery Systems 167
6 Powders and Granules 168
7 Capsules 190
8 Tablets 209
9 Solid Oral Modified-Release Dosage Forms and Drug Delivery Systems 237
Section IV Semisolid Dosage Forms and Transdermal Systems 251
10 Ointments, Creams, and Gels 252
11 Transdermals and Transdermal Drug Delivery Systems 277
Section V Suppositories, Inserts, and Medication Sticks 295
12 Suppositories, inserts, and Medication Sticks 296
Section VI Liquid Dosage Forms 319
13 Solutions 320
14 Disperse Systems 360
Section VII Sterile Dosage Forms and Delivery Systems 409
15 Parenterals 410
16 Biologics 459
17 Special Solutions and Suspensions 478
Section VIII Novel and Advanced Dosage Forms, Delivery Systems, and Devices 503
18 Radiopharmaceuticals 504
19 Products of Biotechnology 529
20 Novel Dosage Forms and Drug Delivery Technologies 565
21 Clinical Pharmaceutics 591
Appendices 607
A Definitions of Selected Drug Categories (Including Those Recognized by USP) 607
B Glossary of Pharmaceutical Terms and Dosage Forms 617
C Systems and Techniques of Pharmaceutical Measurement 623
Index 633
