This book contains 87 papers of the 1989 Symposium on mechanical aspects of blood flow and cardiovascular disease. In the first section clinical studies deal with questions such as heart valve replacement surgical bypass techniques, ultrasound studies in humans and animals, the reaction of pharmaceuticals, and the role of hemodynamic reaction on the endothelial cells. In the second section experimental techniques such as ultrasound, laser-Doppler-anemometry, MRI, and flow visualization are discussed. The hemodynamic environment of the circulatory system cell-cell, cell-wall interactions, endothelial responses to shear stress and other parameters as well as research in the field of rheology is represented in the third section. Finally, these proceedings present notable contributions to the field of numerical study of blood flow parameters. The main goal of this 2nd International Symposium was to bring together physicians, physicists, bioengineers, and technical specialists with experience in clinical, experimental, rheological, and numerical analysis of the complex problems of blood flow and cardiovascular disease. Specialists from 22 countries have taken part.
|Publisher:||Springer Berlin Heidelberg|
|Product dimensions:||6.69(w) x 9.61(h) x 0.05(d)|
Table of ContentsClinical Consideration-Clinical Studies.- Hemodynamically Induced Atrophic Lesions of Atherosclerosis.- What Protects Arm Arteries from Atherosclerosis?.- Analysis of Transcranial Doppler Waves: Pathophysiology of Unilateral Stenoses of the Carotid Artery.- Cerebral Hemodynamic Evaluation by Means of Transcranial Doppler Sonography.- Fluid Dynamical Mechanism of Anacrotic Notch in the Great Arteries.- Radiogrametric Analysis of Carotid Bifurcation: Hemodynamic-Atherogenetic Repercussions on Surgical Patients.- Heart Valve Studies.- Modified Gorlin Equation for the Prediction of Stenotic Valve Orifice Area: An In Vitro Study on a Bioprosthesis.- A Ten Times Enlarged Model of Artificial Heart Valve Flow.- Model Studies at Mechanical Aortic Heart Valve Prostheses in Steady and Physiological Pulsatile Flow.- Direct Measurement of Aortic and Vena Caval Flow to Evaluate the Effect of Vasodilators in Experimental Acute mitral regurgitation.- Echocardiographic and Flow Visualization Studies of the Mechanism for Systolic Anterior Motion of the Mitral Valve In Hypertrophic Cardiomyopathy.- Ultrasound Studies.- The Potential Importance of Arterial Wall Properties and Blood Flow in Relation to Atherogenesis in Essential Hypertension.- Reliability and Problems of Doppler-Sonography in the Assessment of Carotid Stenoses.- The On-line Assessment of Blood Flow Characteristics During Cerebro-vascular Examinations.- A Method of Measuring the Peak Flow-Rate and the Regurgitant Volume of Regurgitation.- Characterization of Pulmonary Artery Blood Velocity Patterns in Lambs.- Detection of Very Early Atherosclerosis by Duplex Sonography.- Normal and Stenotic Blood Flow Velocities in Human Left Coronary Artery Measured by an 80 Channel 20 MHz Pulsed Doppler Velocimeter.- Clinical Studies II.- Von Willebrand Factor Antigen as a Marker of Vascular Injury in Patients with Essential Hypertension.- Hemodynamic and Pathomorphologic Changes of the Aorto-Iliac Arteries Following Unilateral Above Knee Amputation.- Intraoperative Evaluation of Blood Velocity Waveforms in Different Types of Coronary Artery Bypass Grafts-Sequential Saphenous Vein Graft and Internal Mammary Artery Graft.- Hydraulic Conductivity and Shear Dependent Albumin Permeability of Cultured Endothelial Cell Monolayers.- Cellular Recognition and Transduction of Fluid Mechanical Shear Stress Signals.- Animal Studies.- Electrical Impedance of the Carotid Artery in Response to Various Types of Stress.- Morphometry of the Brain Arterial Tree.- Microscopic Visualization of Flow in Rat Cerebral Arteries: Biofluid Dynamical Study on Experimentally Induced Aneurysm.- Effect of the Transmural Pressure on LDL and Albumin Transport and Distribution Across the Intact Arterial Wall.- Areas of High Shear Show Sparing of Lipid Deposition in Hypercholesterolemic Rabbits with Constricted Aortas.- Investigations Concerning Localization of Induced Thrombus Formation at Arteriolar Bifurcations.- MRI and Flow Visualization.- Quantification and Cine Magnetic Resonance Imaging of the Human Blood Flow.- Magnetic Resonance Imaging of Cardiac Blood Flow: An In Vitro Study.- MRI Flow Measurements by a Dynamic Frequency Variation and a flowing Slice Selection.- Visualization of Pulsatile Flow in a Modelled Arterial Anastomosis.- Varicose Meandering: An Indirect Sign of Locally Increased Arterial Flow Transmitted by Arteriovenous Communications (AVCs)?.- Flow Separation Opposite A Side Branch.- The Influence of External Carotid Artery Stenoses on Internal Carotid Artery Flow-An Experimental Investigation.- Experimental Model Studies.- Blood flow Simulations in a Cast of the Aortic Bifurcation.- Wall Shear in a Compliant Cast of a Human Artery Perfused With a Non-Newtonian Fluid, and Its Correlation With Intimal Thickness.- Flow Studies in a Rigid T-Junction Model with a Non-Newtonian Fluid Using a 3-D Laser-Doppler-Anemometer.- Evaluation of Two Fiber Laser Doppler Velocimeter.- Fluid Flow Through Distensible Models of the Carotid Artery Bifurcation.- Separated Flow Demonstrated by Digitized In Vitro Cineangiography Compared with LDV.- Experimental and Numerical Investigation of the Performance and Shear Stresses in a Nutating Centrifugal Blood Pump.- Rheology and Biomaterials.- Effects of n-3 Fatty Acid Supplementation on the Rheological Behavior of Human Blood Measured Ex Vivo.- The Role of Hemorheology in Cerebral Vasospasm Following Subarachnoid Hemorrhage (SAH).- Rheological Analogs for Human Blood in Large Vessels.- Computer Controlled Laser Doppler Velocimeter for Measuring In Vitro Red Cell and Platelet Distributions.- The Influence of Rheological Properties of Test Fluids on the Flow Pattern Inside the Artificial Ventricle (Type Rostock) and in the Aortic Outflow Tract.- Tomographic Analysis of the Effect of Hematocrit on the Distribution of Erythrocytes in Blood Flow in Glass Capillaries of Various Diameters.- Plasma Induced Surface Modification for Medical Application.- Collapsible Tubes.- A Study of Predicted and Experimental Wall Collapse in Models of Highly Stenotic Arteries.- Pressure-Flow Relationships in Partially Occluded Flexible Tubes.- Flow in a Collapsible Tube Connected to Rigid Pipes.- Normal Range of Volume Elastic Modulus in Finger Arteries Determined Indirectly by Electric Impedance-Cuff.- Numerical Studies.- Renal Arterial Stenosis in Renal Transplantation: A Mathematical Pathogenetic Hypothesis and Its Possible Clinical Implications.- A Mathematical Approach to the Development of Arteriosclerosis in Dialysis Patients.- The Role of Wave Reflections in the Ascending Aorta of Man.- Assessment of the Problem of Numerical Simulation of Blood Flow Through Three-Dimensional Bifurcations.- Coronary Blood Flow.- Non-Newtonian Blood Flow Simulation and Wall Shear Stress in an Arterial Bifurcation.- Comparison of Newtonian and Non-Newtonian Blood Flow in Stenotic Vessels using Numerical Simulation.- The Application of Finite Elements Method in the Analysis of Blood Circulation.- Flows Induced by Moving Boundaries and Applications in Biofluid-Mechanics.- Numerical Simulation of Blood Flow Through Branches.- Atherosclerotic Plaques and the Three Dimensional Distribution of Wall Shear Stress-A Numerical Model Study.- Phasic Waveforms of Coronary Arterial and Venous Blood Flow Predicted by a Numerical Model of the Coronary Circulation.- Membrane Phospholipid Metabolism in Sheared Endothelial Cells.- Laser in Biomedical Research, Analysis and Diagnostics.- Problems in the Application of Cardiovascular Models.- Mononuclear Cells Adherence to Aortic Endothelium. The Effect of Transmural Pressure.- The Influence of the Pulsatility and Shear Rate Changes on the Blood Viscosity in Large Vessels.- A Model Fluid for Blood Using Polystyrene Microspheres.- Arterial and Venous Whole Blood- and Plasma Viscosity in Patients with Coronary Heart Disease (CHD).- An Integral-Momentum Approach for the Measurement of Size-Effects in Stenosis for Different Diseases.- Erythrocytic Deformability in Cystic Fibrosis.- Calculation of the Velocity Profile, Flow and Wall Shear Stress in Arteries From the Pressure Gradient: Importance of Distensibility and Taper.- Attenuation of Hydrodynamic Disturbances in Tapered Arterial Prostheses.- Synergetics of Normal and Abnormal Reactions of the Blood In Motion: Fluid-Dynamics, Rheology and Biochemistry.