Bioinformatics and Data Analysis in Microbiology

by Ozlem Tastan Bishop (Editor)

Overview

This book provides invaluable, up-to-date, and detailed information on various aspects of bioinformatics data analysis with applications to microbiology. It describes a number of different useful bioinformatics tools, makes links to some wet-lab techniques, and explains different approaches to tackle a problem. It also talks about current challenges and limitations, gives examples of applications of bioinformatics methods to microbiology, and discusses future trends. The rapid advancement of sequencing techniques, coupled with the new methodologies of bioinformatics to handle large-scale data analysis, are providing exciting opportunities to understand microbial communities from a variety of environments, beyond previous imagination. The chapters in this book include topics such as: genome sequencing techniques * assembly * SNP analysis * annotation * comparative genomics * microbial community profiling * metagenomics * phylogenetic microarrays * barcoding * and more. Bioinformatics and Data Analysis in Microbiology is an essential book for researchers, lecturers, and students involved in microbiology, bioinformatics, and genome analysis. Each chapter is written by experts in the field and is peer-reviewed. [Subject: Microbiology, Bioinformatics, Genomics, Life Science

Product Details

ISBN-13:	9781908230393
Publisher:	Caister Academic Press
Publication date:	04/01/2014
Pages:	270
Product dimensions:	7.09(w) x 9.99(h) x 0.85(d)

Table of Contents

Contributors v

Preface ix

1 Understanding the Unseen Majority Around Us: An Overview of Microbiological Technologies Meesbah Jiwaji Gwynneth F. Matcher Rosemary A. Dorrington 1

2 Prokaryotic Genome Sequencing and Assembly Morag Graham Gary Van Domselaar Paul Stothard 25

3 Genome-wide Variant Discovery Using Sequence Assembly, Mapping and Population-wide Analysis Simone Coughlan Sofia Barreira Cathal Seoighe Tim Downing 51

4 Prokaryotic Genome Annotation Gary Van Domselaar Morag Graham Paul Stothard 81

5 Comparative Analysis of Microbial Pathogen Genomes to Study Unique Gene Families Jade Hotchkiss Nicola J. Mulder 113

6 Microbial Community Profiling: Current Approaches and Future Trends Angel Valverde Pieter De Maayer Don A. Cowan 143

7 Metagenomics and Microbiomes Johannes B. Goll Sebastian Szpakowski Konstantinos Krampis Karen E. Nelson 163

8 Human Microbiome Analysis via the 16s rRNA Gene Jonathan McCafferty Anthony Fodor 193

9 Phylogenetic Microarrays Oleg Paliy Vijay Shankar Marketa Sagova-Mareckova 207

10 Genetic Barcoding of Bacteria and its Microbiology and Biotechnology Applications Oleg N. Reva Wai Y. Chan Oliver K.I. Bezuidt Svitlana V. Lapa Larisa A. Safronova Lilija V. Avdeeva Rainer Borriss 229

Index 245