Calcium Channel Blockers

Calcium Channel Blockers

Paperback(Softcover reprint of the original 1st ed. 2004)

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Overview

The main effect of calcium channel blockers is the blockade of calcium entry into cells through voltage operated calcium channels. This volume gives a comprehensive overview of the different classes of CCBs and their various effects. It covers historical development, pharmacology, clinical aspects, and perspectives. All chapters are written by Prof. T. Godfraind, a world leading expert in the field.

Product Details

ISBN-13: 9783034895996
Publisher: Birkhäuser Basel
Publication date: 11/05/2012
Series: Milestones in Drug Therapy
Edition description: Softcover reprint of the original 1st ed. 2004
Pages: 262
Product dimensions: 6.10(w) x 9.25(h) x 0.02(d)

Table of Contents

Historical perspective: from early steps on calcium research to the identification of calcium antagonist prototypes and of the signaling functions of Ca2+.- Calcium channel blockers and calcium channels.- The action of calcium antagonists on Ca2+ movements in isolated vessels.- The tissue selectivity of calcium antagonists.- Acute haemodynamic effects of calcium channel blockers.- Calcium channels and regulation of vascular tone in hypertension.- Long-term effects of calcium antagonists.- Blood pressure-independent effects of calcium antagonists.- From early clinical studies to randomized controlled clinical trials.- Beyond the cardiovascular system.

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