Deciphering Growth

by J.-C. Carel (Editor), Paul A. Kelly (Editor)

Overview

Growth is a complex process that is essential to life. Not only does size play an important role in the process of cellular proliferation, but body size is also a critical factor in determining which organisms live longer. Evolution has been characterised by a dramatic increase in an organism’s body size, which is not only limited to the size of the brain.

Product Details

ISBN-13:	9783642421297
Publisher:	Springer Berlin Heidelberg
Publication date:	09/24/2014
Series:	Research and Perspectives in Endocrine Interactions
Edition description:	2005
Pages:	155
Product dimensions:	6.10(w) x 9.25(h) x 0.01(d)

Table of Contents

Evolutionary Trends in Body Size.- Sexual Dimorphism in the Growth of Homo sapiens: Facts, Inferences and Speculation.- Genetic Control of Size at Birth.- The GH/IGF-1 Axis: Insights from Animal Models.- Downstream Mechanisms of Growth Hormone Action.- Growth Hormone Receptor Signaling and Differential Actions in Target Tissues Compared to IGF-I.- IGF-I and Brain Growth: Multifarious Effects on Developing Neural Cells and Mechanisms of Action.- IGF-I Deficiency: Lessons from Human Mutations.- Putting IGF-I Biology into a Clinical Perspective.- IGF Resistance: The Role of the Type 1 IGF Receptor.- The Importance of the National Cooperative Growth Study (NCGS).- Why we are Treating Children with Growth Hormone: Lessons from the French Registry.