Diabetes in Practice

by Boris Draznin MD, PhD (Editor)

Overview

In the best tradition of medical practice, this essential text shares a wealth of insight into some of the most challenging diagnoses and clinical experiences from leading diabetologists around the world. Regardless of where a clinician is in their practice, learning never ends. The 49 detailed case studies presented Diabetes in Practice can broaden understanding and elevate patient care across the spectrum of settings. Further, expert commentaries by Mary Korytkowski, MD, Louis Philipson, MD, PhD. Anne Peters, MD, and Boris Draznin, MD, PhD. highlight the important lessons and takeaways from each case. This collection has been carefully curated to enhance diabetes practice, and addresses such topics as: Atypical Diabetes, Diabetic Ketoacidosis (DKA) and Euglycemic DKA, Cancer Therapy and Diabetes, Autoimmunity and Diabetes, Continuous Glucose Monitoring (CGM) and Insulin Pumps, Hypoglycemia, and more.

Product Details

ISBN-13:	9781580407663
Publisher:	American Diabetes Association
Publication date:	08/10/2021
Pages:	304
Product dimensions:	6.00(w) x 9.00(h) x (d)
Age Range:	18 Years

About the Author

Boris Draznin, MD, PhD, is the Celeste and Jack Grynberg Professor of Medicine and Director of the Adult Diabetes Program at the University of Colorado School of Medicine. Dr. Draznin is an internationally known leader in the field of diabetes research and clinical practice. He served as Chair of the Professional Section Advisory Panel of the American Diabetes Association and President of the Western Association of Physicians.

Table of Contents

Preface ix

Part 1 Atypical Diabetes

Case 1 Suspected Maturity-Onset Diabetes of the Young (MODY)-5 (MODY-HNF1B) Responding to Monotherapy with Metformin Ana Ramirez Berlioz, MD Richa Patel, MD David Gardner, MD L. Romayne Kurukulasuriya, AID James Sowers, MD 2

Case 2 Maturity-Onset Diabetes of the Young (MODY)-4 Presenting as Gestational Diabetes Ivana Sheu Yung-In Choi Samar Singh Ping H. Wang 5

Case 3 Does This Patient have Type 1 or Type 2 Diabetes? Zubina Unjom Janice L. Gilden 8

Case 4 Is This an Unusual Type of Diabetes? Nitish Singh Nandu Andriy Havrylyan Janice L. Gilden Bushra Osmani 12

Case 5 Challenges in the Management of Pancreatogenic (Type 3 c) Diabetes Katrina Plan Janet B. McGill 16

Case 6 New-Onset Diabetes as a Symptom of Pancreatic Adenocarcinoma Emily Gammoh Jagdeesh Ullal 20

Case 7 Sweet's Syndrome in a Patient With Diabetes Nitish Singh Nandu Sabah Patel Janice L. Gilden 23

Case 8 Wolcott-Rallison Syndrome Mehmet N. Özbek Eda Cengiz 29

Case 9 Glucose Intolerance Associated with ACTH-Dependent Cushing's Disease Nitya K. Kumar Susan Spratt 33

Case 10 Maturity-Onset Diabetes of the Young (MODY) Misdiagnosis as Steroid-Induced Diabetes Ghada Elshimy Ricardo Correa 37

Part 2 Diabetic Ketoacidosis (DKA) and Euglycemic DKA

Case 11 A Case of Histiocytosis-Lymphadenopathy Plus Syndrome Due to a Novel Mutation in the SLC29A3 Gene and Presentation With Diabetic Ketoacidosis Gül Yesiltepe-Mutlu Mehmet N. Özbek Eda Cengiz 42

Case 12 Acromegaly Presenting With Diabetic Ketoacidosis Ritika Verma K. Huynh R. Gundluru M. Gardner James Sowers 47

Case 13 Rapid-Onset Type 1 Diabetes and Ketoacidosis Deepthi Rimmalapudi Eli Ipp 50

Case 14 Euglycemic Ketoacidosis in the Setting of COVID-19 Infection and Sodium-Glucose Cotransporter 2 Inhibitor Use Olga Duchon Celeste Thomas 54

Case 15 Euglycemic Diabetic Ketoacidosis Due to Sodium-Glucose Cotransporter-2 Inhibitor Use Diana Soliman Nicole Jelesoff 58

Case 16 A Case of Euglycemic Diabetic Ketoacidosis After Initiation of Ketogenic Diet in a Patient With Type 2 Diabetes on a Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor Matthew P. Gilbert Amy Shah 62

Case 17 Diabetic Ketoacidosis in End-Stage Renal Disease: A Unique Challenge Vishnu Garla Angela Subauste Lillian F. Lien 66

Case 18 Euglycemic Diabetic Ketoacidosis in a Patient With Type 1 Diabetes Treated With a Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor While on a Ketogenic Diet Jessica Castellanos-Diaz Julio Leey-Casella Kenneth Cusi Sushma Kadiyala 71

Part 3 Cancer Therapy and Diabetes

Case 19 Immune Checkpoint Inhibitor-Induced Type 1 Diabetes Halis Kaan Akturk Aaron W. Michels 77

Case 20 Partial Β-Cell Destruction: An Atypical Case of Immune Checkpoint Inhibitor Diabetes Zoe Quandt Paras Mehta Katy K. Tsai Victoria Hsiao Robert J. Rushakoff 80

Case 21 Checkpoint Inhibitor-Induced Diabetes Paras Mehta Zoe Quandt Robert J. Rushakoff 83

Case 22 Alpelisib-Induced Hyperglycemia: A Case Series Richa Patel Ana Ramirez Berlioz Amber Pinson Michael Gardner 86

Case 23 Phospharidylinositol 3-Kinase (PI3K) Inhibitor-Induced Hyperglycemia Sanjita B. Chittimoju Sara M. Alexanian Katherine L. Modzelewski 90

Part 4 Autoimmunity and Diabetes

Case 24 Misleading Diabetes: A Case of Type B Insulin Resistance Associated With Lupus Nephritis and Autoimmune Hepatitis Ghada Elshimy Mary Esquivel Meredith McFarland Jessica Ricciuto Christopher Tessier Joanna Miragaya Ricardo Correa 97

Case 25 Latent Autoimmune Diabetes in an Adult With Insulin Allergy Makeda Dawkins Alyson K. Myers 103

Case 26 Onset of Autoimmune Diabetes During Pregnancy Kaitlyn Barrett Kelsey Sheahan Matthew P. Gilbert 107

Case 27 Comorbidity of Diabetes and Systemic Lupus Erythematosus Boris Mankovsky Yanina Saenko 111

Case 28 Illusion of Autoimmune Diabetes Nay Linn Aung 114

Case 29 Can a Lupus Flare Cause Autoimmune Diabetes? Andriy Havrylyan Janice L. Gilden 118

Part 5 Continuous Glucose Monitoring (CGM) and Insulin Pumps

Case 30 Feasibility and Utility of Continuous Glucose Monitoring in an Adult with Type 1 Diabetes and Down's Syndrome Kristen L. Flint Elena Toschi 123

Case 31 A Novel Approach to Achieve Target Time in Range When Using U-500 Regular Insulin in a Continuous Subcutaneous Insulin Infusion (CSLT) Pump Patricia A. Montesinos Michelle F. Magee 127

Case 32 Automated Insulin Infusion System Is Useful to Control Blood Glucose Concentration During Major Stress in Patients with Type 1 Diabetes Renzo Cordera Davide Maggi 132

Case 33 Detecting Patterns in Continuous Glucose Monitoring of Glucocorticoid-Treated Patients With Diabetes Harjyot Sandhu Janice L. Gilden Lynne Wentz 135

Part 6 Hypoglycemia

Case 34 Hyperinsulemic Hypoglycemia After Roux-en-Y Gastric Bypass Surgery: Both Fasting and Postprandial Maria Magar Anne Peters Braden Barnett 143

Case 35 Refractory Hypoglycemia Due to Massive Unintentional Insulin Overdose Jennifer D. Merrill Jennifer Rowell 145

Case 36 A Case of Prolonged Hypoglycemia Due to Sulfonylurea and Concurrent Antibiotic Use Jennifer D. Merrill Susan E. Spratt 150

Part 7 Cystic Fibrosis-Related Diabetes (CFRD)

Case 37 "Do I Really Need Insulin? "The Role of Insulin Therapy in Cystic Fibrosis-Related Diabetes (CFRD) Nader Kasim Antoinette Moran Amir Moheet 155

Case 38 Cystic Fibrosis-Related Diabetes Case Series: Effects of the CF Transmembrane Conductance Regulator (CFTR) Modulator on Glycemic Control Jagdeesh Ullal Lina Merjaneh Kara S. Hughan Andrea Kelly 158

Part 8 Diabetes Management and Miscellaneous Cases

Case 39 Simplifying Insulin Therapy: Transitioning from Basal-Bolus Insulin Therapy to Basal Insulin With a Glucagon-Like Peptide-1 Receptor Analog (GLP-1RA) Sevil Aliyeva Pamela Schroeder Paul Sack 163

Case 40 Simplification of Insulin Regimen Improves Glycemic Control in Elderly Patients With Type 2 Diabetes Maria Gratia Luzuriaga Rajesh Garg 167

Case 41 Effects of Glucagon-Like Peptide-1 Receptor Agonist (GLP- IRA) in an Individual With Type 2 Diabetes on High-Dose Insulin Therapy Basem M. Mishriky Doyle AL Cummings Carlos E. Mendez 171

Case 42 Transient Severe Insulin Resistance in COVID-19 and Prediabetes R. Matthew Hawkins Whitney Adair Joanna Gibbs Jennifer Vinh Cecilia C. Low Wang 175

Case 43 Nondiabetic Renal Disease in Type 1 Diabetes: When to Consider a Renal Biopsy Rong Mei Zhang Ritika Puri Tingting Li Janet B. McGill 179

Case 44 Severe Fetal Malformation Related to Obesity and Type 2 Diabetes Aswathi Kumar Janet B. McGill 184

Case 45 Hyperglycemia from Oral Comfort Feeds Nehu Parimi Rajani Gundluru Michael Gardner James Sowers 188

Case 46 Rethinking Insulin in Type 2 Diabetes Rebecca J. Morey Cynthia Herrick 191

Case 47 Coincidence or Consequence? A Case of Type 1 Diabetes With Worsening Neuropathy Cecilia C. Low Wang 195

Case 48 Challenges to the Management of Diabetes in Patients Who Undergo Ventricular Assist Device (VAD) Implantation Chinenye O. Usoh Donald A. McClain Barbara A. Pisani 199

Case 49 Insulin and Heroin: An Unfortunate Mix in an Overlooked Population Amro Ilaiwy Jennifer V Rowell Beatrice D. Hong 202

Index 205