This thesis establishes a multifaceted extension of the deterministic control framework that has been a workhorse of nonequilibrium statistical mechanics, to shastic, discrete, and autonomous control mechanisms. This facilitates the application of ideas from shastic thermodynamics to the understanding of molecular machines in nanotechnology and in living things. It also gives a scale on which to evaluate the nonequilibrium energetic efficiency of molecular machines, guidelines for designing effective synthetic machines, and a perspective on the engineering principles that govern efficient microscopic energy transduction far from equilibrium. The thesis also documents the author’s design, analysis, and interpretation of the first experimental demonstration of the utility of this generally applicable method for designing energetically-efficient control in biomolecules. Prools designed using this framework systematically reduced dissipation, when compared to naive prools, in DNA hairpins across a wide range of experimental unfolding speeds and between sequences with wildly different physical characteristics.
1139909815
Dissipation and Control in Microscopic Nonequilibrium Systems
This thesis establishes a multifaceted extension of the deterministic control framework that has been a workhorse of nonequilibrium statistical mechanics, to shastic, discrete, and autonomous control mechanisms. This facilitates the application of ideas from shastic thermodynamics to the understanding of molecular machines in nanotechnology and in living things. It also gives a scale on which to evaluate the nonequilibrium energetic efficiency of molecular machines, guidelines for designing effective synthetic machines, and a perspective on the engineering principles that govern efficient microscopic energy transduction far from equilibrium. The thesis also documents the author’s design, analysis, and interpretation of the first experimental demonstration of the utility of this generally applicable method for designing energetically-efficient control in biomolecules. Prools designed using this framework systematically reduced dissipation, when compared to naive prools, in DNA hairpins across a wide range of experimental unfolding speeds and between sequences with wildly different physical characteristics.
199.99
In Stock
5
1

Dissipation and Control in Microscopic Nonequilibrium Systems
236
Dissipation and Control in Microscopic Nonequilibrium Systems
236Paperback(1st ed. 2021)
$199.99
199.99
In Stock
Product Details
ISBN-13: | 9783030858278 |
---|---|
Publisher: | Springer International Publishing |
Publication date: | 10/24/2021 |
Series: | Springer Theses |
Edition description: | 1st ed. 2021 |
Pages: | 236 |
Product dimensions: | 6.10(w) x 9.25(h) x (d) |
About the Author
From the B&N Reads Blog