Overview
In this complete update of their earlier edition, Bates (biological sciences, U. of Liverpool) and Maxwell (biological chemistry, John Innes Center) focus on new research while maintaining their commitment to make the topic approachable and interesting and providing resources for further reading in monographs and other literature. They begin by describing DNA structures, including the Watson-Crick model as well as the B, A, and Z forms and their role in DNA flexibility. They describe DNA supercoiling, including its quantitative measure and the geometrical properties of closed- circular DNA, the behavior of DNA on surfaces, knots and catenanes, DNA topoisomerases, and the biological consequences of DAN topology, including genome organization, replication, control of gene expression, transcription, and recombination. They also provide a helpful glossary. Annotation ©2004 Book News, Inc., Portland, OR
