A strange and very slimy alien invasion takes on a small country community in this horror story. Wheelsy is a small rural town where not much happens, but that's about to change, and not for the better. Grant Grant (Michael Rooker), the town's wealthiest and most powerful citizen, is taking a walk through the woods when he comes across a strange and unfamiliar life form. Grant makes the mistake of getting too close to it, and soon an otherworldly creature has taken over his body. It isn't long before Grant isn't the only one who has been attacked by the strange and slimy things, as a local girl and a handful of house pets go missing. Grant's wife, Starla (Elizabeth Banks), notices that something is very wrong with her husband around the same time that Sheriff Bill Pardy (Nathan Fillion) becomes aware of the pattern of missing people and animals, and they set out to put a stop to the alien invaders intent upon taking over Wheelsy. Slither was the directorial debut for James Gunn, who wrote the screenplay for the 2004 remake of Dawn of the Dead.