Epigenetics of Exercise and Sports: Concepts, Methods, and Current Research

by Stuart M Raleigh (Editor)

Overview

Epigenetics of Exercise and Sports: Concepts, Methods, and Current Research explains fundamental epigenetic processes and how these are altered by exercise and sports. After a brief review of fundamental epigenetic biology, this all-new volume in the Translational Epigenetics series offers step-by-step instruction in how epigenetic factors are investigated for their influence over exercise related traits of human physiology, disease, and injury. The current state of knowledge in the field and recent findings are discussed in-depth, illuminating how exercise and sports performance may epigenetically modify our physiology, disease and injury risks, and how this knowledge can be applied in personalized exercise approaches, diagnostics, and treatment. This book also explores the shortcomings of explaining exercise related phenomena using only genomics and traditional biochemical techniques, setting the scene for a paradigm shift in exercise biology. In addition, over a dozen international specialists contribute chapters on exercise and sports epigenetics, and their influence over metabolism, obesity, aging, immunity, and neurological disease, as well as the epigenetic impacts of concussions and sports doping. A concluding chapter discusses ongoing themes in the field and outlooks for future research.

Product Details

ISBN-13:	9780128206829
Publisher:	Elsevier Science
Publication date:	07/15/2021
Series:	Translational Epigenetics , #25
Pages:	320
Product dimensions:	7.50(w) x 9.25(h) x (d)

About the Author

Stuart M Raleigh, BSc, FIBMS, PhD is an Associate Professor in Exercise Biochemistry and Epigenetics at Coventry University. His research interests focus on epigenetics, genetics, and biochemical mechanisms of chronic disease. He has a special interest in identifying epigenetic factors that influence the risk of musculoskeletal soft tissue pathologies and he is also exploring the link between miRNA expression and various exercise related traits. Dr. Raleigh led the University of Northampton’s Centre for Physical Activity and Chronic Disease (PACD) from 2014-2018 and he has extensive international research collaborations. His teaching interests focus on Alzheimer’s disease and multifactorial genetics. He is a Fellow of the Higher Education Academy (HEA), and Section Editor (Genetics theme) for the Journal of Sports Science and Medicine.

Table of Contents

Section I Concepts and methods
1. Exercise and sport: Definitions, classifications, and relevance to population health
2. Epigenetic processes—An overview
3. Methods to study exercise and sports epigenetics

Section II Current research and future perspectives
4. Nutrients, metabolism, and epigenetic change
5. Obesity epigenetics and exercise
6. Epigenetic change and different types of exercise
7. Exercise, epigenetics, and aging
8. Epigenetics, exercise, and the immune system
9. Alzheimer’s disease, epigenetics, and exercise
10. The current and future state of sports genomics
11. Epigenetic regulation and musculoskeletal injuries
12. Sports concussion and epigenetics
13. Epigenetics and doping in sports—The role of microRNAs
14. Future perspectives and concluding remarks

What People are Saying About This

From the Publisher

Thoroughly examines the influence of sports and exercise over epigenetics processes

Editorial Reviews

Reviewer: Jacob Pfeiffer, DO,MBA(Medical College of Wisconsin)
Description: This book covers what epigenetics is, how it works, and how aging, exercise, sport and even concussion change this. The book is smartly divided into two separate sections: the first being the basics, definitions, and how to measure these things in a laboratory; and the second going over all of the most relevant research on physical activity and epigenetics. There are also sections including sports specifically and future directions.
Purpose: The purpose of this book is to help readers understand the relationship between exercise/sport and epigenetics in hopes to help the population be more active by enabling more customization to exercise and sports for the individual. The objectives are very worthy, and much needed for a population that has over the years become less active, and with fewer results. The book exceeds its objectives by giving a very stepwise education on epigenetics and the ways it plays a role in not only sport, but population exercise.
Audience: This book is written for practitioners, specifically those in sports medicine and lifestyle medicine. While I do believe this is a topic that will continue to gain interest and importance, the in-depth nature of this book may not make it suitable for many students and residents. However, those interested in lifestyle medicine and sports medicine would be wise to learn this information early in their career. The author is a credible authority given his extensive experience in epigenetics and his work with cardiovascular and lifestyle medicine research groups in the U.K.
Features: The book is presented in a very sequential order, starting with basics and definitions of epigenetics and exercise, which for most readers is a necessary aspect to understand. The book then goes into epigenetics and how it can be affected by factors such as exercise, obesity, specific sports, nutrients, aging, and finally pathological states. Finally, the book covers future directions for further research and treatment using epigenetics. The best aspects of the book are the separate sections/chapters going over the research and role of each different variable with epigenetics. The author makes it easy for the novice to understand the concepts. The book does a fantastic job introducing epigenetics, the current research, and the future potential uses.
Assessment: This book is incredibly useful to those in sports, lifestyle, and longevity medicine. It is very well written and laid out thoughtfully for easy reference. To my knowledge, there are no other books that specifically look at epigenetics and sport/exercise for the non-elite athlete. This book can be very useful for guidance, further workups and more for people interested in longevity, and optimization of their health using more than just the normal "diet and exercise."

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