Facilitative Glucose Transporters

by Gwyn W. Gould

Overview

This book is the first comprehensive text covering the major aspects of the cell and molecular biology of the facilitative glucose transporter family. The text reviews the biology and function of each family member, covers structure-function studies, the regulation of glucose transport by insulin and the consequence of diabetes and insulin resistance, discusses aspects of cellular signalling which control glucose transport, reviews the control of expression and function of GLUT2 in liver and pancreatic beta-cells, and reviews the effects of nutrients on the control of sugar transporter expression.

Product Details

ISBN-13:	9780412132919
Publisher:	Springer US
Publication date:	03/15/1997
Series:	Molecular Biology Intelligence Unit Series
Edition description:	1997
Pages:	236
Product dimensions:	7.01(w) x 10.00(h) x 0.02(d)

Editorial Reviews

A detailed overview of facilitative glucose transport in mammalian cells emphasizing research leading to an understanding of the pathophysiology of diabetes or other insulin resistant states. The nine papers introduce the facilitative glucose transporter family, its structure and function, trafficking, targeting, translocation, signaling pathways, GLUT4 in insulin resistance, GLUT2 expression in liver and pancreatic B cells, the nutrient regulation of facilitative hexose transporters, and the regulation of glucose transport by growth factors and oncogenes. Annotation c. by Book News, Inc., Portland, Or.

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