Forensic DNA Analysis: Technological Development and Innovative Applications

by Elena Pilli (Editor), Andrea Berti (Editor)

Overview

Forensic DNA Analysis: Technological Development and Innovative Applications provides a fascinating overview of new and innovative technologies and current applications in forensic genetics. Edited by two forensic experts with many years of forensic crime experience with the Italian police and with prestigious academic universities, the volume takes an interdisciplinary perspective, the volume presents an introduction to genome polymorphisms, discusses, forensic genetic markers, presents a variety of new methods and techniques in forensic genetics, and looks at a selection of new technological innovations and inventions now available from commercial vendors.

The book is an important resource for scientists, researchers, and other experts in the field who will find it of interest for its exhaustive discussion of the most important technological innovations in forensic genetics. For those newer to the field, the volume will be an invaluable reference guide to the forensic world.

Product Details

ISBN-13:	9781774637586
Publisher:	Apple Academic Press
Publication date:	11/01/2022
Pages:	556
Product dimensions:	6.12(w) x 9.19(h) x (d)

About the Author

Elena Pilli, PhD, is a Forensic Molecular Anthropologist and Captain of the Italian Military Police “Carabinieri” at the Forensic Scientific Centre in Rome, Italy, since 2017, a reserve officer selected by CV for her molecular anthropological competence.

Andrea Berti, PhD, is a Forensic Biologist and Lgt. Colonel of the Italian Military Police “Carabinieri” at the Forensic Scientific Centre in Rome, Italy.

Table of Contents

Contributors xi

Abbreviations xv

Foreword xix

Introduction xxi

Part I Introduction to Genome Polymorphisms 1

1 DNA Polymorphisms and Genome Structure: Different Scales of Variation in the Human Genome Andrea Novelletto Bianca Maria Ciminelli 3

2 Single-Nucleotide Polymorphisms: An Overview of the Sequence Polymorphisms Eugenia D'Atanasio Fulvio Cruciani Beniamino Trombetta 23

Part II Forensic Genetic Markers 51

3 Forensic Identity Markers: An Overview of Forensic Autosomal STRs and SNPs Debora Vergani 53

4 The Y-Chromosomal STRs in Forensic Genetics: Y Chromosome STRs Debora Vergani 77

5 The X-Chromosomal STRs in Forensic Genetics: X Chromosome STRs Vânia Pereira Leonor Gusmao 91

6 Application of Mitochondrial DNA as a Tool in the Forensic Field: Update and New Perspectives in mtDNA analysis Manuel Crespillo Márquez Pedro A. Barrio Caballero Carolina Núñez Domingo 113

Part III Novelties in Forensic Genetics 147

7 Sequencing Technology in Forensic Science: Next-Generation Sequencing Runa Daniel SallyAnn Harbison 149

8 Forensic Analysis of Externally Visible Characteristics: Phenotyping Danieie Podini Katherine B. Gettings 201

9 Forensic Ancestry Inference: Data Requirements, Analysis Methods, and Interpretation of Results Ozlem Bulbul Kenneth K. Kidd 225

10 Online Population Data Resources for Forensic SNP Analysis with Massively Parallel Sequencing: An Overview of Online Population Data for Forensic Purposes Christopher Phillips Jorge Amigo Dennis McNevin Maria de la Puente Elaine Y. Y. Cheung Maria Victoria Lareu 241

11 Forensic Anthropology Issues: A Synergy between Physical and Molecular Methods-The Contribution of Degraded DNA Analysis to Physical and Forensic Anthropology Elena Pilli Elisa Castoldi Cristina Cattaneo 289

12 The Molecular Autopsy: Complementary Study to Molecular Autopsy Silvia Zoppis Alejandro Blanco-Verea Maria Brion 337

13 Wildlife Forensics: DNA Analysis in Wildlife Forensic Investigations Rita Lorenzini Luisa Garofalo 357

14 Forensic Entomology: The Utility of Insects at Court and in Human Identification Simonetta Lambiase Aaron M. Tarone 385

Part IV Company Innovations 417

15 Getting the Most Information from Every Sample: Improved Length-Based and Sequence-Based Analysis Rohaizah I. James 419

16 ParaDNA® Technology: A Tool for Rapid Identification of DNA and Body Fluids Laura Dodd Stephanie Regan Tobias Hampshire 433

17 DEPArray™ System: Key Enabling Technology for Cell Separation from Forensic Mixtures Roberta Aversa Francesca Fontana Gianni Medoro Nicolò Manaresi 459

18 Rapid DNA by ANDE Corporation: A Useful Tool for Disaster Victim Identification Rosemary Turingan Witkowski Richard F. Selden 475

19 Massively Parallel Sequencing as an Operational Forensic Tool: Current and Future Perspectives-Improving Results for Current Applications and Paving the Way for Expanded Capabilities Nicola J. Oldroyd Clark Cydne L. Holt 497

Index 523