Genetics: Genes, genomes, and evolution

by Philip Meneely, Rachel D. Hoang, Iruka N. Okeke, Katherine Heston

Overview

In the past, introductory biology courses based on evolution tended to give short shrift to molecular biology. Introductory molecular biology and genetics courses tended to ignore evolutionary principles altogether or included them as concluding chapters that were often skipped. Bacteria were usually treated separately from eukaryotes. Using the analysis of genomes as the organizing approach in Genetics: Genes, Genomes, and Evolution provides the opportunity to unite these topics in one narrative.

Genomic analysis is inherently both molecular and evolutionary, and in Genetics: Genes, Genomes, and Evolution, includes this unified perspective in every chapter. Thus, rather than relying on separate chapters on "genome analysis" or "evolutionary principles" and hoping that the student can synthesize them, these ideas are integrated into every topic.

Product Details

ISBN-13:	9780198712558
Publisher:	Oxford University Press
Publication date:	01/28/2017
Edition description:	New Edition
Product dimensions:	6.00(w) x 1.25(h) x 9.00(d)

About the Author

Philip Meneely is Professor of Biology at Haverford College.

Rachel Dawes Hoang is Associate Professor of Biology at Haverford College.

Iruka N. Okeke is Professor of Pharmaceutical Microbiolog at University of Ibada.

Katherine Heston is Instructor in Biology at Haverford College.

Table of Contents

Prologue: Five Great Ideas

Chapter 1: Evolution, Genomes and Genetics

Chapter 2: The Central Dogma of Molecular Biology

Chapter 3: Genome Organization, Structure, and Variation

Chapter 4: Descent with Modification: DNA Replication and Mutation
A Human Angle: Telomeres
A Human Angle: Analyzing the Black Death by Phylogenetics

Chapter 5: Basic Principles of Single Gene Inheritance

Chapter 6: The Cellular Basis for Mendelian Genetics: Mitosis and Meiosis

Chapter 7: X-linked Genes and Sex Chromosomes
A Human Angle: How Do Organisms Count X Chromosomes?
A Human Angle: Sry, Testis Determining Factor and Sex Determination in Mammals
A Human Angle: X-chromosome Inactivation and Xist

Chapter 8: The Inheritance of Multiple Genes
A Human Angle: ABO Blood Types

Chapter 9: The Location of Genes on Chromosomes: Linkage and Genetic Maps
A Human Angle: Red-Green Colorblindness

Chapter 10: Human Genetic Mapping, GWA Studies and Complex Traits
A Human Angle: Exome Sequencing

Chapter 11: Exchange and Evolution

Chapter 12: Transcription: Reading and Expressing Genes
A Human Angle: Toadstools in the Way of Transcription

Chapter 13: Translation: From Nucleic Acids to Amino Acids

Chapter 14: Networks of Gene Regulation

Chapter 15: Genetic Analysis of Cellular Processes

Chapter 16: The Genetics of Populations
A Human Angle: Tracking Migration with Mitochondrial and Y-chromosome DNA
A Human Angle: The Sickle Cell Trait: Heterozygote Advantage

Chapter 17: Metagenomics: Genomes of Communities
A Human Angle: Transplanting Microbiomes
A Human Angle: Ancient Metagenomes
1. Darwin's Finches: Evolution, Genomes, and Genes
2. The Central Dogma of Molecular Biology
3. Genome Structure, Organization, and Variation
4. Descent with Modification: DNA Replication and Mutation
5. The Inheritance of Single Gene Traits
6. The Cellular Basis for Mendelian Genetics
7. X-linked Genes and Sex Chromosomes
8. The Inheritance of Multiple Genes
9. The Locations of Genes on Chromosomes: Linkage and Genetic Maps
10. Human Genetic Mapping, Genome Wide Association Studies, and Complex Traits
11. Exchange and Evolution
12. Transcription: Reading and Expressing Genes
13. Translation: From Nucleic Acids to Amino Acids
14. Networks of Gene Regulation
15. Genetic Analysis of Cellular Processes
16. The Genetics of Populations
17. Metagenomes: Genome Analysis of Communities