High-Yield Q&A Review for USMLE Step 1: Biochemistry and Genetics

by Michael W. King

Overview

Essential for USMLE Step 1 review!

A rigorous full-color review for any biochemistry or medical biochemistry examination

This full-color review offers a fast and effective way for you to prepare for regular course examinations in biochemistry and medical biochemistry, as well as medical board exams and the USMLE Step 1. A unique feature of this review is the integration of medical biochemistry with physiology, pathophysiology, pathology, and anatomy, making it perfect for today's rapidly changing medical school curriculum. Important related topics such as carbohydrate, lipid, protein metabolism, and associated disease/pathologies are incorporated into a concise, focused review of biochemistry.

High-Yield Q & A Review for USMLE Step 1 is packed with learning aids:

• 1,100 multiple-choice questions and thorough explanations for each answer
• 350 full-color illustrations
• Detailed clinical boxes with high-yield information concerning diseases and disorders related to defects in the pathways being discussed
• Every chapter includes:
   - An outline listing the major topics covered
   - A list of high-yield terms related to the content
   - Numerous explanatory figures and tables designed to increase your understanding of must know material
   - A checklist that recaps important and high-yield concepts

Product Details

ISBN-13:	9781260474046
Publisher:	McGraw Hill LLC
Publication date:	10/24/2022
Pages:	704
Product dimensions:	10.30(w) x 12.20(h) x 1.20(d)

About the Author

Michael W. King, PhD, is associate director for research; Peggy L. Sankey Professor of Medical Education; and professor of biochemistry and molecular biology at Indiana University School of Medicine in Terre-Haute, IN.

Table of Contents

Preface vii

Acknowledgments viii

Part I Foundational BIochemistry 1

1 Biological Building Blocks 1

2 Protein Structure: Hemoglobin and Myoglobin 17

3 Vitamins and Minerals 31

4 Enzymes Kinetics 77

Part II Metabolic Biochemistry 89

5 Glucose, Fructose, and Galactose Metabolism 89

6 Gluconeogenesis 114

7 Glycogen Metabolism 124

8 Pentose Phosphate Pathway 145

9 Pyruvate Dehydrogenase Complex and the TCA Cycle 154

10 Mitochondrial Functions and Oxidative Phosphorylation 163

11 Fatty Acid, Triglyceride, and Phospholipid Synthesis 174

12 Bioactive Lipids and Lipid Mediators 187

13 Lipolysis, Fatty Acid Oxidation, and Ketogenesis 211

14 Ethanol Metabolism 233

15 Cholesterol and Bile Metabolism 243

16 Lipoproteins and Blood Lipids 260

17 Nitrogen Metabolism 278

18 Amino Acid Metabolism 293

19 Amino Acid-Derived Biomolecules 319

20 Nucleotide Metabolism 330

21 Heme Metabolism 347

Part III Cellular and Molecular Biology 365

22 DNA 365

23 Eukaryotic RNA 389

24 Protein Synthesis, Modification, and Targeting 403

25 Cellular Structure and Organization 439

26 Mechanisms of Signal Transduction 471

27 Molecular Biology Tools 487

Part IV Integrative Biochemistry 503

28 Digestive Processes 503

29 Insulin Function 520

30 Diabetes Mellitus 532

31 Peptide and Amino Acid-Derived Hormones 548

32 Steroid and Thyroid Hormones 569

33 Blood Coagulation 592

34 Cancer Biology 610

Part V Medical Genetics 631

35 Medical Genetics 631

Index 669