Human Evolutionary Genetics

Human Evolutionary Genetics (HEG) is a groundbreaking text which for the first time brings together molecular genetics and genomics to the study of the origins and movements of human populations.

Starting with an overview of molecular genomics for the non-specialist (which can be a useful review for those with a more genetic background), the book shows how data from the post-genomic era can be used to examine human origins and the human colonization of the planet, richly illustrated with genetic trees and global maps.

For the first time in a textbook, the authors outline how genetic data and the understanding of our origins which emerges, can be applied to contemporary population analyses, including genealogies, forensics and medicine.

Drawing its material from a range of disciplines, this text is an invaluable resource for courses in:

  • Human Evolution
  • Human Variation
  • Biological Anthropology
  • Physical Anthropology
  • Human Population Genetics
1101587913
Human Evolutionary Genetics

Human Evolutionary Genetics (HEG) is a groundbreaking text which for the first time brings together molecular genetics and genomics to the study of the origins and movements of human populations.

Starting with an overview of molecular genomics for the non-specialist (which can be a useful review for those with a more genetic background), the book shows how data from the post-genomic era can be used to examine human origins and the human colonization of the planet, richly illustrated with genetic trees and global maps.

For the first time in a textbook, the authors outline how genetic data and the understanding of our origins which emerges, can be applied to contemporary population analyses, including genealogies, forensics and medicine.

Drawing its material from a range of disciplines, this text is an invaluable resource for courses in:

  • Human Evolution
  • Human Variation
  • Biological Anthropology
  • Physical Anthropology
  • Human Population Genetics
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Human Evolutionary Genetics

Human Evolutionary Genetics

Human Evolutionary Genetics

Human Evolutionary Genetics

Paperback(Revised)

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Overview

Human Evolutionary Genetics (HEG) is a groundbreaking text which for the first time brings together molecular genetics and genomics to the study of the origins and movements of human populations.

Starting with an overview of molecular genomics for the non-specialist (which can be a useful review for those with a more genetic background), the book shows how data from the post-genomic era can be used to examine human origins and the human colonization of the planet, richly illustrated with genetic trees and global maps.

For the first time in a textbook, the authors outline how genetic data and the understanding of our origins which emerges, can be applied to contemporary population analyses, including genealogies, forensics and medicine.

Drawing its material from a range of disciplines, this text is an invaluable resource for courses in:

  • Human Evolution
  • Human Variation
  • Biological Anthropology
  • Physical Anthropology
  • Human Population Genetics

Product Details

ISBN-13: 9780815341482
Publisher: Taylor & Francis
Publication date: 06/25/2013
Edition description: Revised
Pages: 650
Product dimensions: 8.20(w) x 10.70(h) x 0.90(d)

About the Author

Mark Jobling is a Professor in the Department of Genetics at the University of Leicester, UK. Following a BA in Biochemistry and a DPhil in Genetics from the University of Oxford, he came to Leicester as an MRC Training Fellow in 1992, and has held a Wellcome Trust Senior Fellowship in Basic Biomedical Science since 1999. His research is in the area of human genetic diversity and the forces that pattern it, from mutation processes to cultural factors in human populations. He has a long-term interest in the Y chromosome and its many peculiarities.

Ed Hollox is a Lecturer in the Department of Genetics at the University of Leicester, UK. Following a BA in Natural Sciences from the University of Cambridge and PhD in Genetics from University College London, he spent several years as a postdoc at the University of Nottingham before taking up his current post in 2006. His research interest is the natural genetic diversity of humans and other mammals, in particular the structural variation of genomes.

Matthew Hurles is a Senior Group Leader in Human Genetics at the Wellcome Trust Sanger Institute, Hinxton, UK. Following a BA in Biochemistry from the University of Oxford, he received his PhD in Genetics from the University of Leicester, and established his group at the Wellcome Trust Sanger Institute in 2003. His research interests are in medical and population genetics, with a long term interest in mutation processes and a current focus on the application of genome sequencing to the diagnosis of rare genetic disorders.

Toomas Kivisild is a Reader in the Department of Archaeology and Anthropology, University of Cambridge, UK. He received his PhD from University of Tartu, Estonia, and his earlier research focused on mitochondrial DNA variation in human populations. His current research interests are in human evolution and evolutionary population genetics, with a particular focus on questions relating global genetic population structure with evolutionary processes such as selection, drift, migrations and admixture.

Chris Tyler-Smith heads the Human Evolution team at The Wellcome Trust Sanger Institute, Hinxton, UK. He studied Biochemistry at the University of Oxford and received a PhD form the University of Edinburgh. His research interests include genetic variation in humans and gorillas, and the insights these provide into our evolutionary histories and disease susceptibilities.

Table of Contents

Prefacexvii
Abbrevationsxix
Section 1Introduction1
Chapter 1Why study human evolutionary genetics?3
Section 2How do we study genome diversity?19
Chapter 2Structure, function and inheritance of the human genome21
Chapter 3The diversity of the human genome45
Chapter 4Discovering and assaying genome diversity87
Section 3How do we interpret genetic variation?123
Chapter 5Processes shaping diversity125
Chapter 6Making inferences from diversity153
Section 4Where and when did humans originate?199
Chapter 7Humans as apes201
Chapter 8Origins of modern humans235
Section 5How did humans colonize the world?269
Chapter 9The distribution of diversity--out of Africa and into Asia, Australia and Europe271
Chapter 10Agricultural expansions299
Chapter 11Into new found lands339
Chapter 12What happens when populations meet?373
Section 6How is an evolutionary perspective useful?399
Chapter 13Understanding the past and future of phenotypic variation401
Chapter 14Health implications of our evolutionary heritage439
Chapter 15Identity and identification473
Glossary499
Index515
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