Immune Interferon: Properties and Clinical Applications

by Roumen G. Tsanev, Ivan Ivanov

Overview

Now for the first time, one comprehensive book summarizes and analyzes the numerous scientific papers and reviews covering selected aspects of the structure, biological activities, and clinical effects of immune interferon, also known as interferon-gamma(IFN-gamma). Interferon-gamma is a natural immune booster which has been synthesized and widely used in clinical cases ranging from infectious diseases to cancer, as well as various metabolic disorders. Having developed their own brand of interferon-gamma, the authors are well known in the scientific community. In Immune Interferon: Properties and Clinical Applications, they bring together the extensive findings from twenty years of research since the discovery of the drug. Focusing on the drug itself, and not particular brands, the book presents data on the properties of interferon-gamma, experimental data on its effects, and its clinical applications.

Product Details

ISBN-13:	9780849311482
Publisher:	Taylor & Francis
Publication date:	11/28/2001
Series:	Pharmacology and Toxicology: Basic and Clinical Aspects
Pages:	320
Product dimensions:	6.12(w) x 9.19(h) x (d)

About the Author

Roumen G. Tsanev, Ivan Ivanov

Table of Contents

Foreword. Abbreviations. The Cytokine Family.
Interferon Gamma (IFN). Biological Activities of Interferon Gamma. Molecular Mechanisms of IFN Activities. Transmembrane Signal Transduction. Production of Interferon Gamma. Gamma-Interferon Preparations. Indications and Contraindications. Routes of Administration, Pharmacokinetics, Dosage. Side Effects. Infectious Diseases. Non-Infectious Non-Malignant Diseases. Malignant Diseases. General Conclusions. References.

Editorial Reviews

"…an excellent review of indications studied and under study and the outcomes of IFNg, as well as an exhaustive collection of references for these indications. A briefer overview of the preclinical and pharmacologic aspects of IFNg is provided."
- James E. Talmidge, Ph.D., University of Nebraska Medical School in Doody's Notes

From the Publisher

Two molecular biologists at the Bulgarian Academy of Sciences summarize and critically analyze research findings relating to the antiviral agent and cytokine, interferon gamma, that have been published in the 20 years since its discovery, but not previously compiled into a single-volume reference. They draw data from experiments involving cells cultures and on animals, and from clinical trials regardless of whether or not they show beneficial effects of immune interferon, to present its different properties and its role in different pathological processes. They address doctors, pharmacists, biochemists, and molecular biologists. Annotation c. Book News, Inc., Portland, OR (booknews.com)