The entire scope of the BioMEMS fieldat your fingertips
Helping to educate the new generation of engineers and biologists, Introduction to BioMEMS explains how certain problems in biology and medicine benefit from and often require the miniaturization of devices. The book covers the whole breadth of this dynamic field, including classical microfabrication, microfluidics, tissue engineering, cell-based and noncell-based devices, and implantable systems. It focuses on high-impact, creative work encompassing all the scales of lifefrom biomolecules to cells, tissues, and organisms.
Brilliant color presentation
Avoiding the overwhelming details found in many engineering and physics texts, this groundbreaking bookin color throughoutincludes only the most essential formulas as well as many noncalculation-based exercises. Important terms are highlighted in bold and defined in a glossary. The text contains more than 400 color figures, most of which are from the original researchers.
Coverage of both historical perspectives and the latest developments
Developed from the author’s long-running course, this classroom-tested text gives readers a vivid picture of how the field has grown by presenting historical perspectives and a timeline of seminal discoveries. It also describes numerous state-of-the-art biomedical applications that benefit from "going small," including devices that record the electrical activity of brain cells, measure the diffusion of molecules in microfluidic channels, and allow for high-throughput studies of gene expression.
|Publisher:||Taylor & Francis|
|Edition description:||New Edition|
|Product dimensions:||10.20(w) x 7.30(h) x 0.90(d)|
Table of Contents
How Do We Make Small Things?
Why Bother Making Things Small?
From Art to Chips
Fabrication Based on Self-Assembly: A "Bottom-Up" Approach
Micropatterning of Substrates and Cells
Interaction between Surfaces and Biomolecules
Micropatterns of SAMs
Micropatterns of Proteins
Micropatterns of Cells on Nonbiomolecular Templates
Micropatterns of Cells on Biomolecular Templates
Why Go Small?
Microscale Behavior of Fluids
Fluids in Electrical Fields
Fluids in Acoustic Fields
Fabrication of Microfluidic Channels
Operation of Microfluidic Channels: Practical Concerns
Active Flow Control
Molecular Biology on a Chip
The Importance of Miniaturizing Molecular Biology
The Importance of Point-of-Care Diagnostics: Where is Cost Really, Really, Really Important?
Sample Preparation: A Bloody Example
The Problem with Microfluidic Sample Separation
Chips for Genomics and Proteomics
Electrospray Mass Spectrometry
Biochemical Analysis Using Force Sensors
Cell-Based Chips for Biotechnology
Microfluidic Flow Cytometers
Microfluidic Cell Culture Laboratories
Gene Expression Cellular Microarrays ("Cellomics")
Cells on Microelectrodes
Patch Clamp Chips
Assisted Reproductive Technologies
Whole Animal Testing
BioMEMS for Cell Biology
An Enabling Technology: The Hurdles
BioMEMS for Cellular Neurobiology
Developmental Biology on a Chip
Plant Cell Biology
Microfluidics for Studying Cellular Dynamics
Stem Cell Engineering
Delivery of Soluble Signals into the Body
Microtools for Surgery
A Summary and Further Reading appear at the end of each chapter.