Pub. Date:
Springer Berlin Heidelberg
Ionotropic Glutamate Receptors in the CNS / Edition 1

Ionotropic Glutamate Receptors in the CNS / Edition 1

by Peter Jonas, Hannah Monyer


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Product Details

ISBN-13: 9783540661207
Publisher: Springer Berlin Heidelberg
Publication date: 01/07/2000
Series: Handbook of Experimental Pharmacology , #141
Edition description: 1999
Pages: 535
Product dimensions: 6.10(w) x 9.25(h) x (d)

Table of Contents

Section I: Molecula r Structure of Glutamate Receptors.- 1 Structure of Ionotropic Glutamate Receptors.- 2 Phosphorylation of Glutamate Receptors.- 3 The Synaptic Protein Network Associated with Ionotropic Glutamate Receptors.- 4 Cellular and Subcellular Distribution of Glutamate Receptors.- Section II: Functional Properties of Glutamate Receptors.- 5 Activation of Single AMPA- and NMDA-Type Glutamate-Receptor Channels.- 6 The Ion-Conducting Pore of Glutamate Receptor Channels.- 7 Block of AMPA and Kainate Receptors by Polyamines and Arthropod Toxins.- 8 Kainate Receptors.- 9 Molecular Determinants Controlling Functional Properties of AMPARs and NMDARs in the Mammalian CNS.- Section III: Glutamatergic Synaptic Transmission.- 10 Morphological Characteristics of Glutamatergic Synapses in the Hippocampus.- 11 Glutamate-Mediated Synaptic Excitation of Cortical Interneurons.- 12 Physiology of Glutamatergic Transmission at Calyceal and Endbulb Synapses of the Central Auditory Pathway.- 13 Glutamate Transporters and Their Contributions to Excitatory Synaptic Transmission.- Section IV: Involvement of Glutamate Receptors and Transporters in Neurological Diseases.- 14 Glutamate-Mediated Excitotoxicity.- 15 Glutamate Transporter Dysfunction and Neuronal Death.- 16 NMDA Recepor Antagonists and Their Potential as Neuroprotective Agents.

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