ISBN-10:
0471115940
ISBN-13:
9780471115946
Pub. Date:
06/28/1995
Publisher:
Wiley
The Logic of Chemical Synthesis / Edition 1

The Logic of Chemical Synthesis / Edition 1

by E. J. Corey, Xue-Min Cheng

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Product Details

ISBN-13: 9780471115946
Publisher: Wiley
Publication date: 06/28/1995
Pages: 456
Product dimensions: 7.10(w) x 10.00(h) x 1.00(d)

About the Author

ELIAS JAMES COREY, winner of the 1990 Nobel Prize in Chemistry, is Sheldon Emery Professor in the Department of Chemistry at Harvard University. XUE-MIN CHENG is a Research Associate specializing in cardiovascular medicinal chemistry at Parke-Davis/Warner-Lambert Company.

Table of Contents

GENERAL APPROACHES TO THE ANALYSIS OF COMPLEX SYNTHETICPROBLEMS.

The Basis for Retrosynthetic Analysis.

Transform-Based Strategies.

Structure-Based and Topological Strategies.

Stereochemical Strategies.

Functional Group-Based and Other Strategies.

Concurrent Use of Several Strategies.

SPECIFIC PATHWAYS FOR THE SYNTHESIS OF COMPLEX MOLECULES.

Macrocyclic Structures.

Heterocyclic Structures.

Sesquiterpenoids.

Polycyclic Isoprenoids.

Prostanoids.

Leukotrienes and Other Bioactive Polyenes.

GUIDE TO THE ORIGINAL LITERATURE OF MULTISTEP SYNTHESIS.

Index.

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