Metabolomics: Methods and Protocols

by Wolfram Weckwerth (Editor)

Overview

Metabolomics: Methods and Prools examines the state-of-the-art in metabolomic analysis. Leading researchers in the field present prools for the application of complementary analytical methods, such as gas chromatography-mass spectrometry (GC-MS). Metabolomics: Methods and Prools contains forward-looking prools, which provide the essential groundwork for future efforts in elucidating the structure of the unknowns detected in metabolomic studies.

Product Details

ISBN-13:	9781617376436
Publisher:	Springer-Verlag New York, LLC
Publication date:	11/19/2010
Series:	Methods in Molecular Biology , #358
Edition description:	Softcover reprint of hardcover 1st ed. 2007
Pages:	312
Product dimensions:	5.98(w) x 9.02(h) x 0.35(d)

Table of Contents

Metabolome Analysis Using Gas Chromatography Coupled to Mass Spectrometry.- Metabolite Profiling in Blood Plasma.- Nonsupervised Construction and Application of Mass Spectral and Retention Time Index Libraries From Time-of-Flight Gas Chromatography-Mass Spectrometry Metabolite Profiles.- Metabolomic Profiling of Natural Volatiles.- Metabolomics: Data Integration and Data Mining.- Integrative Profiling of Metabolites and Proteins.- Integrating Profiling Data.- Visualization and Analysis of Molecular Data.- A Gentle Guide to the Analysis of Metabolomic Data.- Capillary Electrophoresis Coupled to Mass Spectrometry.- Capillary Electrophoresis-Mass Spectrometry for Metabolomics.- Liquid Chromatography Coupled to Mass Spectrometry for Metabolomics and Structural Elucidation.- Application of Liquid Chromatography-Mass Spectrometry Analysis in Metabolomics.- Electrochemical Detection of Metabolites.- High-Performance Liquid Chromatography Separations Coupled With Coulometric Electrode Array Detectors.- Metabolic Fluxes.- Determination of Metabolic Flux Ratios From 13C-Experiments and Gas Chromatography-Mass Spectrometry Data.- Understanding the Roadmap of Metabolism by Pathway Analysis.- NMR Metabolome Analysis.- Revealing the Metabolome of Animal Tissues Using 1H Nuclear Magnetic Resonance Spectroscopy.- Nuclear Magnetic Resonance Metabonomics.- Practical Aspects of Uniform Stable Isotope Labeling of Higher Plants for Heteronuclear NMR-Based Metabolomics.

Editorial Reviews

From the reviews:

"This book forms part of an extensive and successful series from Methods in Molecular Biology … . this book provides a good introduction to metabolomics, with useful prools and relevant data analysis techniques that can be adapted easily to suit any researcher’s needs." (Elizabeth Want, ChemMedChem, Issue 2, 2007)

From the Publisher