Molecular Diagnostics

by Anthony Warford (Editor), Nadege Presneau (Editor)

Overview

One of the most notable trends in biomedical science in recent years has been the increasing use of molecular techniques as part of the diagnosis of disease. As such, there is a growing need for students to understand the technological basis of molecular analysis and to have a comprehensive appreciation of their use in diagnosis. Combining coverage of molecular techniques with their application to diagnostic pathology, this book provides students with a thorough and up to date appreciation of the scope of molecular analysis, the principles of the technology used, and thematic diagnostic application.

As part of the Fundamentals of Biomedical Science series, the book provides a unique blend of theory and practice, featuring a range of learning features to help students assimilate the information presented quickly and effectively. It will be relevant to undergraduate students on a wide variety of biomedical pathways, cutting across traditional discipline boundaries to provide a unified overview of molecular diagnostics.

Product Details

ISBN-13:	9780198777069
Publisher:	Oxford University Press, USA
Publication date:	06/12/2019
Series:	Fundamentals of Biomedical Science
Pages:	344
Product dimensions:	7.44(w) x 9.69(h) x 0.87(d)

About the Author

Anthony Warford, Emeritus Fellow, Department of Biomedical Sciences, University of Westminster,Nadege Presneau, Senior Lecturer in Biomedical Sciences, University of Westminster

Anthony Warford is Emeritus Fellow in the Department of Biomedical Sciences at the University of Westminster, Fellow of the Institute of Biomedical Sciences, and Chartered Scientist. He is the primary author of two scientific papers on tissue microarray, two reviews on in situ hybridisation, and a book chapter on same subject, as well as being a co-author of many other papers. He has lectured internationally on immunohistochemistry and in situ hybridisation.

Nadege Presneau is Senior Lecturer in the Department of Biomedical Sciences at the University of Westminster. She teaches Molecular Pathology and Cancer Genetics/Genomics at undergraduate and postgraduate levels. Her research focuses principally on developing new bioinformatics approaches to identify driver genes involved in breast cancer using high throughput technologies such as Next Generation Sequencing. She is also interested in the development of new diagnostic tools for cancer as well as biobanking and ethics in translational research.

Table of Contents

Introduction, Anthony Warford and Nadege Presneau
1. Sample preparation, Anthony Warford and Sandra Hing
2. The molecular laboratory, Sandra Hing and Anthony Warford
3. Intact sample analysis, Anthony Warford and Emanuela V Volpi
4. Homogenate sample analysis, Nadege Presneau, Abdul Hye, and Nicholas Ashton
5. Sequencing technologies, Nadege Presneau and Rifat Hamoudi
6. Molecular analysis and interpreting molecular data, Rifat Hamoudi and Anthony Warford
7. Recent technical advances in molecular analysis, Nadege Presneau and Mary Alikian
8. Haemopoietic diseases 1 - leukaemias, Georgina Ryland and Piers Blombery
9. Haemopoietic diseases 2 - lymphoproliferative disorders, Mark Catherwood and Ken Mills
10. Breast cancer, Mary Falzon, Elaine Borg, and Alexandra Saetta
11. Epithelial tumours and melanoma, Manuel Rodriguez-Justo
12. Mesenchymal tumours, Fernanda Amary
13. Pre-natal and neo-natal testing, Claire V.S. Brasted-Pike