Neoplastic Diseases of the Blood / Edition 4

by Peter H. Wiernik, John M. Goldman, Janice P. Dutcher, Robert A. Kyle

Overview

In this fourth edition of the classic work on malignant blood cancers, the team of editors and over 100 international leaders in the field provide a comprehensive text on the diagnosis and treatment of all hematologic malignancies, both common and rare. This extensively revised and updated edition reflects the tremendous progress in the science and treatment of hematologic malignancies during the eight years since the third edition. Revisions and new chapters include coverage of stem cell transplantation, molecular genetics, monoclonal antibodies, and new treatment modalities.

Product Details

ISBN-13:	9780521791366
Publisher:	Cambridge University Press
Publication date:	06/28/2003
Edition description:	Revised Edition
Pages:	1214
Product dimensions:	8.86(w) x 11.38(h) x 2.60(d)

About the Author

Peter H. Wiernik, MD, Doctor HC
Cancer Research Foundation, Chappaqua, NY, USA


Janice P. Dutcher, MD
Cancer Research Foundation, Chappaqua, NY, USA


Morie A. Gertz, MD
Mayo Clinic, Department of Hematology, Rochester, MN, USA

Table of Contents

Part I. Chronic Leukemias and Related Disorders: 1. A history of the chronic leukemias; 2. Epidemiology of the chronic leukemias; 3. Pathology and morphology of chronic leukemias and related disorders; 4. Molecular biology and cytogenetics of chronic myeloid leukemia; 5. Diagnosis and treatment of chronic myeloid leukemia; 6. Molecular biology and cytogenetics of chronic lymphocytic leukemia; 7. Diagnosis and treatment of chronic lymphocytic leukemia; 8. Diagnosis and treatment of hairy cell leukemia; 9. The pathogenesis, diagnosis and treatment of polycythaemia vera; 10. Diagnosis and treatment of essential thrombocythemia and chronic idiopathic myelofibrosis; Part II. Acute Leukemias: 11. Historical perspectives; 12. Human t-cell lymphoma/leukemia virus associated t-cell lymphoma and leukemia; 13. Epidemiology and hereditary aspects of acute leukemia; 14. Classification of the acute leukemias: cytochemical and morphologic considerations; 15. Immunobiology of acute leukemia; 16. Cytogenetics of acute leukemia; 17. Diagnosis and treatment of childhood acute lymphoblastic leukemia; 18. Diagnosis and treatment of adult acute lymphoblastic leukemia; 19. Diagnosis and treatment of childhood acute myelogenous leukemia; 20. Diagnosis and treatment of adult acute myeloid leukemia other than acute promyelocytic leukemia; 21. Acute promyelocytic leukemia; 22. Therapy-related acute myelogenous leukemia; 23. Myelodysplastic syndromes; Part III. Myeloma and Related Disorders: 24. History of multiple myeloma; 25. Cytokines and signal transduction in multiple myeloma; 26. Epidemiology of multiple myeloma; 27. Immunoglobins and laboratory recognition of monoclonal proteins; 28. Cytogenetic abnormalities in the monoclonal gammopathies; 29. Molecular genetics in multiple myeloma and related disorders; 30. Staging, kinetics and prognosis in multiple myeloma; 31. Diagnosis and treatment of multiple myeloma; 32. Syndromes and special presentations associated with plasma cell myeloma; 33. Waldenstrom's macroglobulinemias; 34. Heavy-chain disease; 35. Amyloidosis; 36. Monoclonal gammopathies of undetermined significance; Part IV. Lymphoma: 37. Historical overview of malignant lymphoma; 38. Etiology of lymphoma and Hodgkin's disease; 39. Epidemiology and hereditary aspects of malignant lymphoma and Hodgkin's disease; 40. Pathology of non-Hodgkin's lymphomas and Hodgkin's disease; 41. Immunology of the lymphomas; 42. Cytogenetics of non-Hodgkin lymphoma and Hodgkin disease; 43. Diagnosis and treatment of Hodgkin's disease; 44. Radiotherapeutic management of lymphomas; 45. Diagnosis and treatment of non-Hodgkin's lymphoma of adults; 46. Non-Hodgkin's lymphoma of childhood; 47. Lymphoma in other diseases; Part V. Supportive Care: 48. Historical perspectives; 49. Prevention of infection in patients with hematological malignancies; 50. Evaluation and management of bacterial and fungal infections occurring in patients with hematological malignancy; 51. Viral infections in patients with hematological malignancies; 52. Therapeutic cytapheresis and plasma exchange; 53. Red cell transfusions in patients with hematologic malignancies; 54. Platelet and granulocyte transfusion; 55. Stem cell processing and purging; 56. Alternative sources of hemopoietic stem cells and their clinical applications; 57. Umbilical cord stem cell transplantation; 58. HLA typing in hematopoietic cell transplantation; 59. Special care of blood and marrow stem cell transplant patients; 60. Hematopoietic growth factors in the supportive care and treatment of patients with hematologic malignancies; 61. Bleeding and thrombosis in hematologic neoplasia; 62. Psychological aspects of hematological malignancies.

Editorial Reviews

"...well organized, well written and...well illustrated." Oncology

"One of the best (if not the best) general reference sources on the clinical aspects of hematologic neoplastic diseases." New England Journal of Medicine

"Neoplastic Diseases of the Blood is a classic text that would be an excellent addition to the library of anyone interested in a comprehensive book that integrates the history, epidemiology, pathology, pathophysiology, and therapeutics of modern neoplastic hematopathology." American Journal of Clinical Pathology

"Without question, this is the most comprehensive, almost encyclopaedic textbook on leukaemias, myeloproliferative and myelodysplastic syndromes and lymphomas presently available. As stated in the preface, it was the editors' aim to design an encyclopaedic resource for established haematologists and medical oncologists taking care of adults and children. The reviewer believes that this aim has been achieved magnificently. This is a carefully edited, very good book, and nothing comparable is on the market." Annals of Oncology, D.K. Hossfeld, Hamburg, Germany

From the Publisher

**** An encyclopedic resource for hematologists and oncologists as well as fellows in those subspecialties, cited in Brandon-Hill. This edition is revised and updated to reflect the progress in the understanding of the nature and treatment of hematologic malignancies since the second edition of 1991. Five new chapters are included, on the diagnosis and treatment of acute promyelocytic leukemia; molecular genetics in multiple myeloma and related disorders; procurement, processing, and storage of marrow for transplantation; alternative sources of hematopoietic stem cells and their applications; and psychosocial management of patients with hematologic malignancies. Annotation c. Book News, Inc., Portland, OR (booknews.com)

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