Oxford Textbook of Neuromuscular Disorders

by David Hilton-Jones, Martin Turner

Overview

Part of the Oxford Textbooks in Clinical Neurology series, the Oxford Textbook of Neuromuscular Disorders covers the scientific basis, clinical diagnosis, and treatment of neuromuscular disorders with a particular focus on the most clinically relevant disorders. The book is organized into seven sections, starting with the general approach to the patient with neuromuscular disorders and then focusing on specific neuromuscular conditions affecting the peripheral nervous system from its origins at the spinal cord anterior horn on its outward course to their effector muscles and the inbound sensory pathways. Chapters on specific neuromuscular conditions are illustrated with typical case histories and their presenting features, allowing readers to put rarer conditions into their clinical context more easily. The concurrent online version allows access to the full content of the textbook, contains links from the references to primary research journal articles, allows full text searches, and provides access to figures and tables that can be downloaded to PowerPointRG.
This textbook will serve as a useful reference for neurologists and specialist trainees in neurology, neuroscientists, neurophysiologists, and other healthcare professionals.

Product Details

ISBN-13:	9780199698073
Publisher:	Oxford University Press
Publication date:	07/01/2014
Series:	Oxford Textbooks in Clinical Neurology
Pages:	400
Product dimensions:	8.80(w) x 11.00(h) x 0.80(d)

About the Author

David Hilton-Jones, Consultant Neurologist, Department of Clinical Neurology, Department of Neurosciences, John Radcliffe Hospital, Oxford, UK,Martin Turner, Consultant Neurologist, Department of Clinical Neurology, Department of Neurosciences, John Radcliffe Hospital, Oxford, UK

Dr David Hilton-Jones is Consultant Neurologist at the University of Oxford and John Radcliffe Hospital, Oxford UK and Clinical Director, Muscular Dystrophy Campaign Muscle and Nerve Centre. Dr Hilton-Jones developed an interest in muscle diseases when working for Dr John Morgan-Hughes at Queen Square, London before spending a year training with the late Professor George Karpati in Montreal. He was appointed as a consultant neurologist in Oxford, UK with the intention of developing services for patients with neuromuscular disorders and is now Clinical Director of the Oxford Muscle & Nerve Centre, supported by the Muscular Dystrophy Campaign. He is also Clinical Director of the Oxford Myasthenia Centre, supported by the Myasthenia Gravis Association. His major interest is in combining clinical practice and research.



Dr Martin Turner is a Consultant Neurologist and Senior Clinician Scientist within the Oxford University Nuffield Department of Clinical Neurosciences. His research focuses on understanding the variation in the clinical presentations of amyotrophic lateral sclerosis/motor neuron disease (ALS/MND) and finding biomarkers for them. In particular Dr Turner is interested in the role of the brain in ALS/MND, and using advanced neuroimaging to explore structure and function through his affiliation with the Oxford Centre for the Functional Magnetic Resonance Imaging of the Brain: FMRIB.

Table of Contents

Section 1: Approach to the patient1. Eliciting the history, David Hilton-Jones and Martin R. Turner2. Genetic considerations, David Hilton-Jones and Martin R. Turner3. Examination, David Hilton-Jones and Martin R. TurnerSection 2: Anterior Horn4. Amyotrophic Lateral Sclerosis, Kevin Talbot and Martin R. Turner5. Spinal muscular atrophy and hereditary motor neuropathy, Dirk Baumer and Kevin Talbot6. Kennedy's disease, Kenneth Fischbeck and Christopher Grunseich7. Poliomyelitis, Robin S. HowardSection 3: Peripheral Nerve: Inherited8. Charcot Marie Tooth disease, Mary Reilly and Alex Rossor9. Hereditary sensory and autonomic neuropathies, Michaela Auer-Grumbach10. Familial amyloid polyneuropathy, Violaine Plante-Bordeneuve11. Inherited metabolic neuropathies, Lionel GinsbergSection 4: Peripheral Nerve: Acquired12. Mononeuropathies, Neil G Simon and Matthew C Kiernan13. Multiple mononeuropathies, J Gareth Llewelyn and Eleanor A Marsh14. Plexopathy, David LH Bennett and Mohamed Mahdi-Rogers15. Polyneuropathies: Axonal, Camiel Verhamme and Ivo N van Schaik16. Polyneuropathies: Demyelinating, Pieter A van Doorn and Judith Drenthen17. Diabetic neuropathy, Stephen A Goutman, Andrea L. Smith, Stacey A. Sakowski, and Eva L. Feldman18. Peripheral nerve hyperexcitability disorders, David Hilton-JonesSection 5: Neuromuscular Junction: Inherited and Acquired19. Inherited myasthenic syndromes, Jackie Palace and Sarah Finlayson20. Myasthenia gravis, Saiju Jacob, Stuart Viegas, and David Hilton-Jones21. The Lambert-Eaton myasthenic syndrome, Maarten J. Titulaer and Jan J G M VerschuurenSection 6: Muscle22. The dystrophinopathies, Kevin M. Flanagan23. Limb-girdle muscular dystrophies, Fiona Norwood and Kate Bushby24. The congenital muscular dystrophies, Emma Clement and Heinz Jungbluth25. The myotonic dystrophies, David Hilton-Jones and Chris Turner26. FSH dystrophy, Baziel Van Engelen, Elly van der Kooi, and Silvere van der Maarel27. Distal myopathies and myofibrillar myopathies, Bjarne Udd28. Congenital/ultrastructural myopathies, Gianina Ravenscroft, Nigel F. Clarke, and Nigel G. Liang29. Metabolic myopathies, John Vissing and Mette Orngreen30. Mitochondrial cytopathies, Gerald Pfeffer and Patrick F. Chinnery31. Skeletal muscle channelopathies, Emma Matthews and Michael G. Hanna32. Idiopathic inflammatory myopathies, Marianne de Visser and Anneke J. van der Kooi33. Drug-induced neuromuscular disorders, Zohar Argov34. Endocrine myopathies, Merrilee Needham and Frank MastagliaSection 7: Acute neuromuscular consults35. The neuromuscular emergency consult, Peter Connick and Maxwell S. Damian36. Critical care of neuromuscular disorders, Maxwell S Damian